High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MCF7 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 608 285 image if available 12711 40214 295.5 67.78 143.73 163.15 209 239 260 277 293 309 328 350 384 0.0353 1418 1.016 119.62 46.69 2 0.0271 344 0.0013 26.32 6.921 0.2277 91894.8
30000000
10200000000
3620000000000
0.4370 0.2187 0.0000 0.0000 0.0011 0.0000 0.0043 0.0006 0.0194 0.0020 0.0643 0.0160 0.1388 0.0422 0.1306 0.0429 0.1606 0.0610 0.4809 0.8354 0.0000 0.0000 0.0003 0.0000 0.0008 0.0001 0.0053 0.0011 0.0274 0.0105 0.0590 0.0245 0.0510 0.0194 0.0701 0.0291 0.7861 0.9154 0.0071 0.0128 0.0075 0.0192 0.0179 0.0417 0.0613 0.1330 0.1289 0.1875 0.1811 0.2051 0.1097 0.0865 0.1506 0.1330 0.3358 0.1811 0.0008 0.0024 0.0064 0.0265 0.0750 0.1260 0.1010 0.1299 0.5321 11 17 28 49 80 122 178 254 371 0.0435 17.85 5.232 0.4864 47276.4
22300000
13100000000
8910000000000
0.4347 0.1843 0.0559 0.0013 0.1725 0.0173 0.2681 0.1183 0.1475 0.1465 0.1431 0.1771 0.0944 0.1809 0.0533 0.1241 0.0376 0.1058 0.0276 0.1288 0.0001 0.0001 0.0004 0.0006 0.0019 0.0015 0.0116 0.0097 0.0649 0.0509 0.1109 0.0898 0.0752 0.0672 0.1098 0.0956 0.6253 0.6846 0.0006 0.0007 0.0011 0.0013 0.0036 0.0075 0.0213 0.0276 0.0840 0.0988 0.1417 0.1531 0.0910 0.0952 0.1254 0.1330 0.5313 0.4828 0.0003 0.0013 0.0032 0.0164 0.0787 0.1225 0.0861 0.1208 0.5707
MCF 10A Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 346 701 image if available 14198 40387 106.4 32.10 146.17 188.92 72 82 90 96 103 110 118 129 144 0.0393 1589 0.755 201.22 48.27 2 0.0373 529 0.0026 18.07 6.363 0.2881 12345.6
1580000
229000000
39000000000
0.4708 0.1852 0.0007 0.0001 0.0041 0.0010 0.0119 0.0011 0.0333 0.0042 0.0850 0.0218 0.1598 0.0539 0.1708 0.0533 0.1970 0.0847 0.3372 0.7798 0.0002 0.0000 0.0011 0.0001 0.0015 0.0003 0.0096 0.0013 0.0331 0.0130 0.0687 0.0281 0.0706 0.0210 0.1052 0.0352 0.7101 0.9010 0.0061 0.0103 0.0105 0.0240 0.0243 0.0326 0.0723 0.1021 0.1348 0.1501 0.1713 0.1827 0.1203 0.1226 0.1413 0.1389 0.3190 0.2367 0.0017 0.0051 0.0119 0.0353 0.0818 0.1125 0.1127 0.1276 0.5114 12 14 17 21 38 97 181 289 433 0.0636 63.25 5.587 0.4594 57055.8
29900000
18300000000
12600000000000
0.5337 0.1336 0.0936 0.0033 0.2406 0.0356 0.2573 0.2023 0.1157 0.1813 0.1154 0.1677 0.0874 0.1514 0.0464 0.0816 0.0283 0.0770 0.0152 0.0996 0.0002 0.0000 0.0009 0.0004 0.0022 0.0010 0.0084 0.0066 0.0488 0.0425 0.1001 0.0859 0.0667 0.0576 0.0957 0.0872 0.6770 0.7188 0.0006 0.0001 0.0009 0.0017 0.0039 0.0037 0.0107 0.0152 0.0648 0.0721 0.1272 0.1439 0.0905 0.0989 0.1204 0.1231 0.5809 0.5414 0.0005 0.0010 0.0023 0.0103 0.0565 0.1095 0.0807 0.1143 0.6250
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1103 521 image if available 38572 41531 83.7 70.09 7.10 2.74 45 48 50 53 56 62 73 98 152 0.0457 1898 0.782 128.16 45.34 3 0.0101 390 0.0492 1.50 4.084 0.6882 11919.8
2870000
920000000
334000000000
0.4510 0.1895 0.0109 0.0089 0.0164 0.0172 0.0246 0.0246 0.0351 0.0389 0.0605 0.0504 0.0801 0.0590 0.0958 0.0673 0.1409 0.0885 0.5357 0.6452 0.0040 0.0067 0.0055 0.0130 0.0089 0.0188 0.0105 0.0286 0.0183 0.0354 0.0237 0.0412 0.0271 0.0468 0.0418 0.0594 0.8604 0.7500 0.0015 0.0009 0.0027 0.0019 0.0047 0.0041 0.0104 0.0090 0.0173 0.0159 0.0259 0.0282 0.0314 0.0309 0.0401 0.0398 0.8660 0.8695 0.0020 0.0024 0.0056 0.0088 0.0174 0.0214 0.0294 0.0366 0.8764 4 5 6 6 7 8 8 9 11 0.4747 0.33 1.180 0.8414 57.9
527.37
5295.83
58155.7
0.4995 0.1829 0.0184 0.0024 0.0723 0.0096 0.1551 0.0301 0.2242 0.0749 0.2394 0.1555 0.1742 0.2423 0.0889 0.2556 0.0251 0.1713 0.0024 0.0583 0.0022 0.0001 0.0106 0.0010 0.0291 0.0053 0.0623 0.0178 0.1060 0.0556 0.1606 0.1162 0.2066 0.1940 0.2316 0.2914 0.1910 0.3187 0.0905 0.1632 0.1612 0.2060 0.1796 0.1882 0.1754 0.1469 0.1412 0.1102 0.1007 0.0685 0.0624 0.0461 0.0489 0.0412 0.0401 0.0296 0.0110 0.0392 0.0830 0.1233 0.1517 0.1724 0.1677 0.1502 0.1015
MCF 10A Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 536 592 image if available 11784 41678 115.6 34.59 207.83 214.61 75 86 94 103 111 120 130 144 163 0.0416 1732 0.727 154.55 39.40 3 0.0386 455 0.0021 19.63 6.518 0.2766 14550.8
1990000
293000000
46400000000
0.4899 0.1699 0.0021 0.0004 0.0048 0.0007 0.0141 0.0032 0.0416 0.0077 0.1062 0.0329 0.1621 0.0738 0.1591 0.0708 0.1647 0.0991 0.3453 0.7113 0.0007 0.0001 0.0018 0.0005 0.0040 0.0013 0.0122 0.0039 0.0406 0.0176 0.0687 0.0392 0.0628 0.0280 0.0796 0.0464 0.7295 0.8631 0.0022 0.0025 0.0041 0.0115 0.0137 0.0329 0.0504 0.0873 0.1067 0.1853 0.1530 0.1919 0.1278 0.1227 0.1467 0.1524 0.3956 0.2133 0.0013 0.0036 0.0085 0.0266 0.0690 0.1142 0.0929 0.1140 0.5699 15 20 37 80 139 203 278 375 515 0.0215 74.38 6.685 0.3397 89248.9
51000000
34800000000
27200000000000
0.4252 0.2362 0.0235 0.0012 0.1173 0.0073 0.2179 0.0568 0.1485 0.1081 0.1623 0.1648 0.1467 0.2023 0.0826 0.1340 0.0615 0.1331 0.0396 0.1923 0.0003 0.0001 0.0006 0.0004 0.0028 0.0018 0.0089 0.0066 0.0493 0.0407 0.0985 0.0784 0.0722 0.0592 0.0927 0.0831 0.6748 0.7298 0.0013 0.0008 0.0022 0.0025 0.0046 0.0081 0.0169 0.0211 0.0664 0.0802 0.1232 0.1307 0.0875 0.0958 0.1112 0.1158 0.5867 0.5449 0.0005 0.0023 0.0051 0.0144 0.0596 0.1114 0.0778 0.1061 0.6229
Hs 578T
0
DRAQ5 1 TMRE 2 2 2 1 334 363 image if available 15302 41714 244.9 60.87 131.95 179.42 171 196 213 227 242 257 273 292 320 0.0338 1411 0.710 67.01 10.63 1 0.0092 141 0.0009 32.33 7.369 0.2155 63663.8
17500000
5040000000
1520000000000
0.3811 0.2520 0.0003 0.0001 0.0018 0.0001 0.0054 0.0012 0.0129 0.0025 0.0443 0.0131 0.0775 0.0277 0.0883 0.0259 0.1303 0.0318 0.6391 0.8975 0.0001 0.0000 0.0009 0.0000 0.0019 0.0005 0.0043 0.0006 0.0157 0.0082 0.0271 0.0149 0.0311 0.0107 0.0502 0.0147 0.8688 0.9504 0.0040 0.0021 0.0074 0.0094 0.0148 0.0178 0.0415 0.0545 0.0820 0.1027 0.1180 0.1394 0.0981 0.1038 0.1164 0.1153 0.5177 0.4549 0.0010 0.0043 0.0084 0.0193 0.0357 0.0673 0.0704 0.0887 0.7048 13 17 21 29 47 80 136 229 381 0.0427 30.07 5.192 0.5095 49598.6
28100000
20000000000
16800000000000
0.3211 0.3337 0.0612 0.0021 0.1948 0.0183 0.2759 0.1123 0.1692 0.1501 0.1266 0.2025 0.0897 0.1912 0.0381 0.1170 0.0295 0.0975 0.0151 0.1089 0.0001 0.0001 0.0003 0.0005 0.0017 0.0013 0.0140 0.0104 0.0568 0.0497 0.0959 0.0827 0.0647 0.0548 0.0965 0.0855 0.6699 0.7149 0.0002 0.0004 0.0005 0.0012 0.0029 0.0045 0.0170 0.0211 0.0778 0.0843 0.1185 0.1332 0.0800 0.0874 0.1208 0.1226 0.5822 0.5453 0.0002 0.0013 0.0024 0.0139 0.0650 0.1091 0.0726 0.1074 0.6281
Hs 578T Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 420 407 image if available 25302 42176 171.8 49.38 147.43 237.23 112 132 146 157 168 180 193 209 237 0.0462 1948 0.760 83.49 25.63 2 0.0098 247 0.0005 62.65 7.913 0.1534 31965.7
6390000
1360000000
309000000000
0.4638 0.1892 0.0006 0.0001 0.0017 0.0002 0.0040 0.0010 0.0225 0.0052 0.0688 0.0183 0.1379 0.0386 0.1421 0.0455 0.1734 0.0654 0.4489 0.8256 0.0003 0.0000 0.0009 0.0001 0.0012 0.0003 0.0082 0.0023 0.0254 0.0102 0.0549 0.0202 0.0570 0.0218 0.0776 0.0313 0.7745 0.9136 0.0031 0.0052 0.0063 0.0083 0.0203 0.0270 0.0520 0.0513 0.0941 0.0896 0.1249 0.1265 0.0922 0.0926 0.1087 0.1087 0.4984 0.4909 0.0012 0.0029 0.0075 0.0285 0.0609 0.0972 0.0953 0.1135 0.5931 15 18 20 25 35 63 116 226 460 0.1298 9.91 4.162 0.6635 78010.9
64000000
64700000000
75200000000000
0.5804 0.1109 0.0461 0.0048 0.1404 0.0150 0.1993 0.0735 0.1444 0.1068 0.1579 0.1632 0.1301 0.1918 0.0879 0.1258 0.0525 0.1221 0.0414 0.1970 0.0003 0.0004 0.0022 0.0006 0.0037 0.0016 0.0126 0.0129 0.0488 0.0445 0.0771 0.0675 0.0547 0.0498 0.0753 0.0744 0.7252 0.7484 0.0003 0.0004 0.0020 0.0030 0.0029 0.0043 0.0165 0.0197 0.0624 0.0647 0.0891 0.0998 0.0647 0.0673 0.0892 0.0949 0.6728 0.6458 0.0008 0.0012 0.0033 0.0140 0.0563 0.0848 0.0591 0.0848 0.6958
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 692 185 image if available 19415 44441 368.7 56.02 244.04 276.54 299 324 341 357 370 384 398 414 438 0.0403 1792 0.714 124.33 24.70 1 0.0157 305 0.0014 22.18 6.923 0.2357 139081.0
53500000
21000000000
8390000000000
0.4311 0.2269 0.0001 0.0000 0.0008 0.0001 0.0028 0.0001 0.0066 0.0002 0.0259 0.0087 0.0530 0.0182 0.0576 0.0109 0.0865 0.0176 0.7667 0.9443 0.0001 0.0000 0.0004 0.0001 0.0011 0.0001 0.0033 0.0002 0.0141 0.0084 0.0282 0.0172 0.0273 0.0090 0.0375 0.0134 0.8880 0.9517 0.0119 0.0000 0.0209 0.0000 0.0346 0.0000 0.0930 0.0000 0.1169 0.0000 0.1574 0.0000 0.1199 0.0000 0.1306 0.0000 0.3148 0.0000 0.0012 0.0035 0.0100 0.0254 0.0509 0.0848 0.0988 0.1192 0.6061 17 22 30 54 118 220 341 473 647 0.0281 44.65 6.124 0.4266 136024.0
100000000
87800000000
88300000000000
0.4534 0.1804 0.0700 0.0020 0.2411 0.0134 0.3304 0.1499 0.1469 0.1951 0.0898 0.2149 0.0610 0.1886 0.0354 0.0976 0.0173 0.0724 0.0080 0.0662 0.0003 0.0002 0.0010 0.0004 0.0018 0.0013 0.0092 0.0076 0.0506 0.0416 0.1014 0.0881 0.0667 0.0543 0.0944 0.0803 0.6746 0.7262 0.0007 0.0004 0.0014 0.0017 0.0031 0.0043 0.0147 0.0194 0.0670 0.0789 0.1259 0.1392 0.0883 0.0943 0.1136 0.1275 0.5852 0.5343 0.0001 0.0007 0.0030 0.0105 0.0587 0.1131 0.0775 0.1049 0.6315
Hs 578T A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 798 428 image if available 27432 45118 211.1 59.97 98.82 173.21 140 162 179 194 208 223 239 258 287 0.0427 1927 0.804 104.04 21.19 1 0.0082 226 0.0007 43.54 7.545 0.1862 48158.5
11800000
3050000000
838000000000
0.4170 0.2298 0.0009 0.0000 0.0014 0.0001 0.0072 0.0005 0.0254 0.0026 0.0661 0.0188 0.1224 0.0410 0.1361 0.0439 0.1737 0.0674 0.4667 0.8259 0.0003 0.0000 0.0006 0.0000 0.0027 0.0001 0.0072 0.0009 0.0239 0.0093 0.0448 0.0189 0.0494 0.0177 0.0650 0.0292 0.8061 0.9239 0.0049 0.0049 0.0082 0.0175 0.0196 0.0265 0.0469 0.0746 0.0894 0.1169 0.1266 0.1677 0.1090 0.1102 0.1271 0.1250 0.4683 0.3566 0.0014 0.0023 0.0066 0.0227 0.0535 0.0917 0.0877 0.1135 0.6206 10 12 14 16 20 29 54 137 332 0.1819 23.17 3.891 0.6587 39767.1
24100000
17400000000
14100000000000
0.4082 0.2647 0.1462 0.0039 0.3078 0.0465 0.2795 0.2378 0.1040 0.2151 0.0818 0.2042 0.0463 0.1441 0.0206 0.0647 0.0093 0.0494 0.0046 0.0343 0.0000 0.0000 0.0009 0.0006 0.0015 0.0011 0.0142 0.0095 0.0704 0.0604 0.0987 0.0930 0.0678 0.0551 0.1104 0.0943 0.6360 0.6860 0.0003 0.0000 0.0017 0.0017 0.0033 0.0043 0.0185 0.0216 0.0848 0.0897 0.1211 0.1251 0.0804 0.0863 0.1188 0.1212 0.5710 0.5502 0.0001 0.0006 0.0030 0.0167 0.0751 0.1185 0.0740 0.1117 0.6002
Hs 578T A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 487 388 image if available 17803 45389 157.0 50.28 154.36 177.24 92 114 128 142 155 168 183 200 225 0.0425 1928 1.251 24.52 7.81 5 0.0033 58 0.0011 27.12 7.140 0.2383 27189.4
5090000
1010000000
213000000000
0.4282 0.2106 0.0016 0.0001 0.0027 0.0011 0.0080 0.0022 0.0288 0.0083 0.0923 0.0292 0.1552 0.0530 0.1536 0.0615 0.1813 0.0892 0.3764 0.7554 0.0006 0.0001 0.0008 0.0008 0.0020 0.0012 0.0062 0.0038 0.0238 0.0118 0.0466 0.0193 0.0520 0.0202 0.0673 0.0299 0.8006 0.9130 0.0028 0.0076 0.0051 0.0076 0.0145 0.0286 0.0373 0.0753 0.0821 0.1201 0.1345 0.1711 0.1117 0.1287 0.1381 0.1368 0.4740 0.3241 0.0009 0.0019 0.0057 0.0186 0.0505 0.0897 0.0859 0.1121 0.6346 13 18 26 47 81 128 193 278 407 0.0395 20.75 5.394 0.5005 55240.7
27700000
16900000000
11900000000000
0.4247 0.2143 0.0378 0.0014 0.1492 0.0110 0.2622 0.0683 0.1893 0.1171 0.1504 0.1913 0.1095 0.1978 0.0586 0.1383 0.0341 0.1296 0.0088 0.1451 0.0003 0.0002 0.0011 0.0008 0.0022 0.0018 0.0130 0.0095 0.0518 0.0406 0.0919 0.0720 0.0661 0.0535 0.0987 0.0822 0.6750 0.7394 0.0006 0.0006 0.0012 0.0024 0.0051 0.0080 0.0184 0.0254 0.0735 0.0834 0.1248 0.1314 0.0862 0.0949 0.1190 0.1284 0.5712 0.5254 0.0004 0.0015 0.0030 0.0169 0.0596 0.1071 0.0813 0.1092 0.6210
MCF7 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 234 799 image if available 13982 47347 267.6 72.72 111.48 151.15 180 206 227 244 261 277 298 324 366 0.0290 1375 0.637 134.38 29.41 4 0.0255 356 0.0013 25.91 6.963 0.2170 76872.3
23600000
7750000000
2700000000000
0.4326 0.2214 0.0001 0.0000 0.0013 0.0001 0.0055 0.0004 0.0221 0.0029 0.0806 0.0231 0.1501 0.0550 0.1533 0.0526 0.1827 0.0775 0.4043 0.7885 0.0000 0.0000 0.0003 0.0000 0.0018 0.0002 0.0076 0.0010 0.0363 0.0137 0.0660 0.0277 0.0623 0.0230 0.0865 0.0394 0.7392 0.8952 0.0052 0.0034 0.0097 0.0101 0.0207 0.0151 0.0446 0.0772 0.1034 0.1394 0.1383 0.2065 0.0906 0.0999 0.1317 0.1360 0.4557 0.3123 0.0005 0.0028 0.0097 0.0328 0.0738 0.1215 0.0977 0.1158 0.5454 7 9 11 16 39 79 133 204 314 0.0819 10.81 4.504 0.5328 35272.3
16700000
10300000000
7940000000000
0.3283 0.3071 0.0637 0.0018 0.1924 0.0219 0.2593 0.1299 0.1590 0.1336 0.1409 0.1843 0.0919 0.1786 0.0492 0.1220 0.0306 0.1122 0.0130 0.1156 0.0001 0.0000 0.0004 0.0004 0.0007 0.0005 0.0071 0.0063 0.0513 0.0394 0.0875 0.0698 0.0707 0.0553 0.1096 0.0865 0.6726 0.7417 0.0003 0.0002 0.0010 0.0011 0.0030 0.0057 0.0155 0.0207 0.0717 0.0816 0.1258 0.1367 0.0873 0.0954 0.1313 0.1337 0.5642 0.5249 0.0001 0.0005 0.0021 0.0105 0.0627 0.1064 0.0809 0.1220 0.6149
SK-BR-3 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 969 728 image if available 16378 49009 195.5 37.68 203.96 331.62 151 169 180 189 198 206 215 226 241 0.0278 1362 1.188 93.09 34.48 1 0.0143 235 0.0032 12.80 6.161 0.3225 39638.5
8270000
1770000000
387000000000
0.4222 0.2262 0.0002 0.0000 0.0012 0.0000 0.0037 0.0000 0.0129 0.0003 0.0346 0.0080 0.0661 0.0181 0.0824 0.0160 0.1152 0.0268 0.6836 0.9309 0.0001 0.0000 0.0003 0.0000 0.0008 0.0000 0.0036 0.0001 0.0120 0.0068 0.0260 0.0139 0.0283 0.0069 0.0418 0.0107 0.8870 0.9616 0.0089 0.0576 0.0166 0.0995 0.0426 0.1047 0.0736 0.1780 0.1192 0.1937 0.1473 0.1675 0.1256 0.0733 0.1456 0.0890 0.3206 0.0366 0.0012 0.0027 0.0072 0.0202 0.0501 0.0834 0.0821 0.1197 0.6333 7 8 10 12 17 54 192 390 701 0.1432 35.53 4.788 0.5519 151568.0
149000000
169000000000
211000000000000
0.4292 0.2197 0.0529 0.0035 0.2034 0.0131 0.2775 0.1127 0.1544 0.1604 0.1262 0.2014 0.0909 0.1979 0.0516 0.1081 0.0322 0.1003 0.0110 0.1027 0.0001 0.0001 0.0003 0.0001 0.0010 0.0003 0.0081 0.0057 0.0395 0.0371 0.0691 0.0641 0.0487 0.0414 0.0700 0.0648 0.7633 0.7864 0.0004 0.0003 0.0011 0.0011 0.0028 0.0036 0.0129 0.0138 0.0452 0.0466 0.0753 0.0825 0.0565 0.0561 0.0729 0.0789 0.7329 0.7170 0.0001 0.0013 0.0022 0.0102 0.0423 0.0730 0.0512 0.0723 0.7473
Hs 578T A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 224 664 image if available 23929 53243 235.7 71.53 198.53 308.24 140 172 197 217 235 254 274 298 328 0.0344 1829 0.641 165.59 39.45 7 0.0212 508 0.0005 51.67 7.813 0.1685 60653.4
16700000
4890000000
1500000000000
0.4168 0.2169 0.0013 0.0002 0.0025 0.0005 0.0085 0.0016 0.0313 0.0057 0.0797 0.0252 0.1433 0.0530 0.1429 0.0600 0.1764 0.0821 0.4142 0.7718 0.0006 0.0002 0.0010 0.0003 0.0020 0.0007 0.0074 0.0028 0.0227 0.0123 0.0429 0.0258 0.0415 0.0237 0.0600 0.0321 0.8218 0.9020 0.0018 0.0071 0.0045 0.0102 0.0154 0.0252 0.0432 0.0885 0.0873 0.1322 0.1280 0.1588 0.1107 0.1225 0.1340 0.1433 0.4752 0.3123 0.0008 0.0021 0.0061 0.0159 0.0445 0.0832 0.0794 0.1112 0.6569 15 19 23 31 50 98 191 331 581 0.0417 56.38 5.497 0.4839 134424.0
143000000
193000000000
306000000000000
0.3773 0.2809 0.0950 0.0031 0.2742 0.0340 0.2930 0.1903 0.1326 0.1923 0.0925 0.1954 0.0613 0.1542 0.0320 0.0969 0.0146 0.0718 0.0047 0.0620 0.0002 0.0002 0.0007 0.0005 0.0028 0.0019 0.0151 0.0118 0.0675 0.0598 0.1124 0.0965 0.0779 0.0655 0.1108 0.0997 0.6126 0.6642 0.0005 0.0011 0.0017 0.0024 0.0055 0.0069 0.0244 0.0283 0.0804 0.0894 0.1332 0.1361 0.0938 0.0992 0.1210 0.1267 0.5395 0.5097 0.0004 0.0016 0.0031 0.0214 0.0760 0.1177 0.0887 0.1187 0.5725
SK-BR-3 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 518 503 image if available 15648 56021 320.9 59.50 142.33 181.99 244 279 299 315 329 341 354 368 389 0.0239 1341 0.987 126.85 36.01 1 0.0202 316 0.0015 21.65 6.855 0.2488 106538.0
36300000
12600000000
4480000000000
0.4413 0.2040 0.0005 0.0000 0.0005 0.0000 0.0020 0.0000 0.0079 0.0003 0.0295 0.0078 0.0562 0.0157 0.0615 0.0104 0.0915 0.0162 0.7503 0.9496 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0023 0.0003 0.0109 0.0075 0.0242 0.0143 0.0210 0.0081 0.0316 0.0119 0.9098 0.9580 0.0090 0.0536 0.0157 0.0179 0.0336 0.1429 0.0745 0.2143 0.1272 0.1429 0.1557 0.1607 0.1429 0.1071 0.1597 0.0357 0.2818 0.1250 0.0008 0.0025 0.0050 0.0158 0.0410 0.0684 0.0815 0.0977 0.6873 8 10 12 18 51 108 178 269 424 0.1076 16.66 4.969 0.5393 53375.8
26600000
15300000000
9680000000000
0.3694 0.2725 0.0166 0.0013 0.1012 0.0060 0.2168 0.0361 0.1910 0.0912 0.1770 0.1724 0.1403 0.2115 0.0824 0.1547 0.0457 0.1475 0.0291 0.1792 0.0006 0.0002 0.0006 0.0006 0.0027 0.0015 0.0085 0.0065 0.0354 0.0299 0.0682 0.0565 0.0555 0.0459 0.0719 0.0641 0.7567 0.7947 0.0005 0.0005 0.0022 0.0022 0.0040 0.0048 0.0126 0.0154 0.0463 0.0551 0.0837 0.0934 0.0695 0.0743 0.0862 0.0911 0.6950 0.6633 0.0005 0.0017 0.0041 0.0114 0.0416 0.0737 0.0613 0.0797 0.7260
Hs 578T Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 903 431 image if available 54613 82874 84.8 46.65 114.00 205.41 23 28 54 73 87 99 112 126 146 0.0303 2514 0.607 231.82 52.47 24 0.0118 645 0.0046 13.65 6.351 0.3627 9367.0
1190000
165000000
24700000000
0.5125 0.1476 0.0017 0.0007 0.0076 0.0010 0.0380 0.0040 0.0801 0.0150 0.1435 0.0575 0.1828 0.1084 0.1675 0.1062 0.1626 0.1362 0.2163 0.5709 0.0002 0.0000 0.0004 0.0000 0.0014 0.0002 0.0055 0.0015 0.0213 0.0119 0.0388 0.0234 0.0374 0.0198 0.0551 0.0316 0.8399 0.9117 0.0006 0.0018 0.0028 0.0048 0.0065 0.0130 0.0229 0.0391 0.0576 0.0808 0.0882 0.1189 0.0857 0.0985 0.1117 0.1228 0.6241 0.5203 0.0004 0.0014 0.0040 0.0124 0.0339 0.0605 0.0589 0.0824 0.7461 10 12 13 15 18 26 61 174 383 0.2390 19.16 3.787 0.6638 55186.4
40400000
36400000000
37700000000000
0.4605 0.1949 0.1576 0.0035 0.3814 0.0611 0.3071 0.3277 0.0839 0.2234 0.0408 0.1726 0.0158 0.1086 0.0071 0.0487 0.0039 0.0298 0.0026 0.0245 0.0001 0.0001 0.0006 0.0003 0.0013 0.0008 0.0117 0.0106 0.0652 0.0602 0.1027 0.0939 0.0640 0.0575 0.0983 0.0881 0.6561 0.6885 0.0000 0.0004 0.0009 0.0009 0.0020 0.0025 0.0164 0.0184 0.0742 0.0778 0.1173 0.1225 0.0764 0.0817 0.1085 0.1098 0.6044 0.5860 0.0001 0.0002 0.0017 0.0132 0.0722 0.1105 0.0693 0.1056 0.6272