LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 658 3349 3846 0.8709 0.8443
Hs 578T Lapatinib
0.04
uM
LJP6
 72
hr
 658 3543 3846 0.9213 0.9050
Hs 578T LDN-193189
0.04
uM
LJP5
 72
hr
 658 3797 3846 0.9874 0.9848
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 658 3770 3846 0.9802 0.9761
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 658 3634 3846 0.9450 0.9337
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 658 707 3846 0.1838 0.0153
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 658 605 3846 0.1575 -0.0165
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 658 3276 3846 0.8519 0.8213
Hs 578T Neratinib
0.04
uM
LJP5
 72
hr
 658 3377 3846 0.8780 0.8529
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 658 4075 3846 1.0597 1.0720
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9246 0.9090
Hs 578T NU7441
0.04
uM
LJP5
 72
hr
 658 3759 3846 0.9774 0.9728
Hs 578T Dactolisib
0.04
uM
LJP5
 72
hr
 658 1163 3846 0.3026 0.1586
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 658 3080 3846 0.8008 0.7597
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 658 2361 3846 0.6140 0.5343
Hs 578T PD0325901
0.04
uM
LJP5
 72
hr
 658 2312 3846 0.6013 0.5190
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 658 2223 3846 0.5782 0.4911
Hs 578T PD173074
0.04
uM
LJP6
 72
hr
 658 3362 3846 0.8743 0.8484
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 658 3334 3846 0.8669 0.8395
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 658 3894 3846 1.0125 1.0150
Hs 578T PF431396
0.04
uM
LJP5
 72
hr
 658 2917 3846 0.7584 0.7086
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 658 3621 3846 0.9416 0.9295
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 658 3389 3846 0.8813 0.8568
Hs 578T PHA-665752
0.04
uM
LJP5
 72
hr
 658 4007 3846 1.0418 1.0505
Hs 578T PHA-793887
0.04
uM
LJP6
 72
hr
 658 1834 3846 0.4768 0.3688