LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TGX221 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3799 | 4223 | 0.8996 | 0.8497 |
| SK-BR-3 | Torin1 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1306 | 4223 | 0.3094 | -0.0336 |
| SK-BR-3 | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1047 | 4223 | 0.2480 | -0.1255 |
| SK-BR-3 | Tozasertib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1562 | 4223 | 0.3700 | 0.0571 |
| SK-BR-3 | Trametinib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3614 | 4223 | 0.8559 | 0.7843 |
| SK-BR-3 | TWS119 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1527 | 4223 | 0.3617 | 0.0446 |
| SK-BR-3 | Vemurafenib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3594 | 4223 | 0.8510 | 0.7770 |
| SK-BR-3 | Withaferin A | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1018 | 4223 | 0.2411 | -0.1359 |
| SK-BR-3 | Withaferin A | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1153 | 4223 | 0.2731 | -0.0880 |
| SK-BR-3 | WYE-125132 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1467 | 4223 | 0.3474 | 0.0232 |
| SK-BR-3 | WZ3105 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 992 | 4223 | 0.2349 | -0.1451 |
| SK-BR-3 | XMD11-50 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1955 | 4223 | 0.4629 | 0.1962 |
| SK-BR-3 | Y39983 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1540 | 4223 | 0.3647 | 0.0491 |
| SK-BR-3 | YM 201636 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1942 | 4223 | 0.4599 | 0.1917 |
| SK-BR-3 | ZSTK474 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1564 | 4223 | 0.3705 | 0.0578 |