LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 2449 | 4223 | 0.5799 | 0.3712 |
| SK-BR-3 | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 2176 | 4223 | 0.5154 | 0.2747 |
| SK-BR-3 | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 2324 | 4223 | 0.5504 | 0.3271 |
| SK-BR-3 | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3210 | 4223 | 0.7603 | 0.6412 |
| SK-BR-3 | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1087 | 4223 | 0.2576 | -0.1112 |
| SK-BR-3 | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1345 | 4223 | 0.3185 | -0.0200 |
| SK-BR-3 | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1190 | 4223 | 0.2819 | -0.0749 |
| SK-BR-3 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1199 | 4223 | 0.2839 | -0.0718 |
| SK-BR-3 | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 878 | 4223 | 0.2080 | -0.1854 |
| SK-BR-3 | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1099 | 4223 | 0.2603 | -0.1071 |
| SK-BR-3 | PI103 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1348 | 4223 | 0.3193 | -0.0189 |
| SK-BR-3 | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 2797 | 4223 | 0.6623 | 0.4946 |
| SK-BR-3 | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1228 | 4223 | 0.2909 | -0.0614 |
| SK-BR-3 | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1099 | 4223 | 0.2604 | -0.1070 |
| SK-BR-3 | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1094 | 4223 | 0.2591 | -0.1089 |
| SK-BR-3 | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 1401 | 922 | 4223 | 0.2185 | -0.1697 |
| SK-BR-3 | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 2209 | 4223 | 0.5232 | 0.2863 |
| SK-BR-3 | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3908 | 4223 | 0.9255 | 0.8885 |
| SK-BR-3 | XL147 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3703 | 4223 | 0.8770 | 0.8159 |
| SK-BR-3 | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 1401 | 2100 | 4223 | 0.4974 | 0.2478 |
| SK-BR-3 | Selumetinib | 10.0 | uM | LJP6 | 72 | hr | 1401 | 4192 | 4223 | 0.9927 | 0.9891 |
| SK-BR-3 | Sirolimus | 10.0 | uM | LJP6 | 72 | hr | 1401 | 2532 | 4223 | 0.5997 | 0.4009 |
| SK-BR-3 | Sorafenib | 10.0 | uM | LJP6 | 72 | hr | 1401 | 2693 | 4223 | 0.6378 | 0.4578 |
| SK-BR-3 | SU11274 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1480 | 4223 | 0.3505 | 0.0278 |
| SK-BR-3 | Fedratinib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1116 | 4223 | 0.2643 | -0.1011 |