LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1659 | 4223 | 0.3930 | 0.0915 |
| SK-BR-3 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1271 | 4223 | 0.3010 | -0.0461 |
| SK-BR-3 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 2006 | 4223 | 0.4752 | 0.2145 |
| SK-BR-3 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4388 | 4223 | 1.0392 | 1.0587 |
| SK-BR-3 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1367 | 4223 | 0.3239 | -0.0120 |
| SK-BR-3 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1506 | 4223 | 0.3566 | 0.0370 |
| SK-BR-3 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4204 | 4223 | 0.9956 | 0.9934 |
| SK-BR-3 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1913 | 4223 | 0.4531 | 0.1814 |
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1523 | 4223 | 0.3608 | 0.0433 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1652 | 4223 | 0.3913 | 0.0889 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1499 | 4223 | 0.3550 | 0.0345 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3763 | 4223 | 0.8911 | 0.8369 |
| SK-BR-3 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4115 | 4223 | 0.9746 | 0.9619 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4944 | 4223 | 1.1707 | 1.2555 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 4181 | 4223 | 0.9901 | 0.9852 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 4047 | 4223 | 0.9584 | 0.9377 |
| SK-BR-3 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1401 | 2635 | 4223 | 0.6240 | 0.4373 |
| SK-BR-3 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 4107 | 4223 | 0.9726 | 0.9590 |
| SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4034 | 4223 | 0.9553 | 0.9331 |
| SK-BR-3 | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3441 | 4223 | 0.8150 | 0.7231 |
| SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4142 | 4223 | 0.9808 | 0.9713 |
| SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1512 | 4223 | 0.3582 | 0.0394 |
| SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1188 | 4223 | 0.2814 | -0.0756 |
| SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1451 | 4223 | 0.3437 | 0.0177 |
| SK-BR-3 | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3405 | 4223 | 0.8064 | 0.7102 |