LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 929 | 4060 | 3228 | 1.2579 | 1.3622 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4479 | 3694 | 1.2127 | 1.3543 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1657 | 6867 | 5505 | 1.2473 | 1.3538 |
| Hs 578T | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 929 | 3939 | 3228 | 1.2202 | 1.3093 |
| Hs 578T | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 929 | 3923 | 3228 | 1.2155 | 1.3026 |
| Hs 578T | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3913 | 3228 | 1.2123 | 1.2981 |
| MCF7 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 5022 | 4156 | 1.2085 | 1.2967 |
| Hs 578T | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 929 | 3899 | 3228 | 1.2079 | 1.2920 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 4341 | 3694 | 1.1751 | 1.2918 |
| SK-BR-3 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4337 | 3694 | 1.1741 | 1.2901 |
| Hs 578T | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 929 | 3894 | 3228 | 1.2063 | 1.2897 |
| BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 1657 | 6589 | 5505 | 1.1969 | 1.2817 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4313 | 3694 | 1.1676 | 1.2793 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4309 | 3694 | 1.1665 | 1.2773 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4294 | 3694 | 1.1624 | 1.2706 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 4293 | 3694 | 1.1621 | 1.2701 |
| MCF7 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4937 | 4156 | 1.1880 | 1.2676 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4284 | 3694 | 1.1598 | 1.2662 |
| MCF7 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4925 | 4156 | 1.1851 | 1.2633 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4915 | 4156 | 1.1827 | 1.2600 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4269 | 3694 | 1.1557 | 1.2594 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4899 | 4156 | 1.1787 | 1.2543 |
| Hs 578T | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 929 | 3812 | 3228 | 1.1810 | 1.2542 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4251 | 3694 | 1.1508 | 1.2512 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4880 | 4156 | 1.1743 | 1.2481 |