LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 3.33 | uM | LJP6 | 72 | hr | 513 | 351 | 10401 | 0.0338 | -0.0164 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 584 | 4156 | 0.1405 | -0.2230 |
| MCF 10A | A443654 | 0.12 | uM | LJP6 | 72 | hr | 513 | 2023 | 10401 | 0.1946 | 0.1527 |
| MCF 10A | A443654 | 1.11 | uM | LJP6 | 72 | hr | 513 | 445 | 10401 | 0.0428 | -0.0069 |
| MCF7 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 982 | 4156 | 0.2364 | -0.0865 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 790 | 4156 | 0.1901 | -0.1525 |
| Hs 578T | A443654 | 10.0 | uM | LJP6 | 72 | hr | 929 | 684 | 3228 | 0.2119 | -0.1067 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 72 | hr | 513 | 4000 | 10401 | 0.3846 | 0.3527 |
| MCF 10A | A443654 | 0.37 | uM | LJP6 | 72 | hr | 513 | 692 | 10401 | 0.0666 | 0.0181 |
| BT-20 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 652 | 5505 | 0.1185 | -0.2613 |
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 72 | hr | 513 | 415 | 10401 | 0.0400 | -0.0099 |
| MCF7 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1024 | 4156 | 0.2464 | -0.0724 |
| MCF7 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 838 | 4156 | 0.2017 | -0.1359 |
| Hs 578T | A443654 | 0.04 | uM | LJP6 | 72 | hr | 929 | 2096 | 3228 | 0.6494 | 0.5077 |
| Hs 578T | A443654 | 0.37 | uM | LJP6 | 72 | hr | 929 | 952 | 3228 | 0.2950 | 0.0100 |
| Hs 578T | A443654 | 1.11 | uM | LJP6 | 72 | hr | 929 | 719 | 3228 | 0.2227 | -0.0915 |
| BT-20 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 1495 | 5505 | 0.2716 | -0.0422 |
| Hs 578T | A443654 | 0.12 | uM | LJP6 | 72 | hr | 929 | 1547 | 3228 | 0.4794 | 0.2690 |
| BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1142 | 5505 | 0.2075 | -0.1339 |
| BT-20 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 2897 | 5505 | 0.5262 | 0.3221 |
| BT-20 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 2386 | 5505 | 0.4334 | 0.1894 |
| BT-20 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1225 | 5505 | 0.2225 | -0.1125 |
| Hs 578T | A443654 | 3.33 | uM | LJP6 | 72 | hr | 929 | 638 | 3228 | 0.1976 | -0.1267 |
| MDA-MB-231 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 868 | 1292 | 3486 | 0.3706 | 0.1619 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 748 | 4156 | 0.1801 | -0.1666 |