LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 1 | H07 | 72 | hr | 1694 | 99 | 11155 | 0.0089 | -0.1686 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 2 | H07 | 72 | hr | 1694 | 106 | 11155 | 0.0095 | -0.1679 |
| Hs 578T | HG-6-64-01 | 10.0 | uM | LJP6 | 1 | M01 | 72 | hr | 765 | 123 | 3124 | 0.0394 | -0.2721 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 3 | H07 | 72 | hr | 1694 | 142 | 11155 | 0.0127 | -0.1641 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP6 | 3 | C19 | 72 | hr | 765 | 163 | 3124 | 0.0522 | -0.2552 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 2 | C19 | 72 | hr | 765 | 165 | 3124 | 0.0528 | -0.2543 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 765 | 170 | 3124 | 0.0544 | -0.2522 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 765 | 174 | 3124 | 0.0557 | -0.2505 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 765 | 177 | 3124 | 0.0566 | -0.2492 |
| Hs 578T | AT-7519 | 10.0 | uM | LJP6 | 1 | K01 | 72 | hr | 765 | 179 | 3124 | 0.0573 | -0.2484 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP6 | 1 | G01 | 72 | hr | 765 | 182 | 3124 | 0.0582 | -0.2471 |
| BT-20 | CGP60474 | 10.0 | uM | LJP6 | 1 | G01 | 72 | hr | 1334 | 182 | 3970 | 0.0458 | -0.4372 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 765 | 186 | 3124 | 0.0595 | -0.2454 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 765 | 186 | 3124 | 0.0595 | -0.2454 |
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 1 | G01 | 72 | hr | 1694 | 192 | 11155 | 0.0172 | -0.1588 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 2 | C20 | 72 | hr | 765 | 196 | 3124 | 0.0627 | -0.2412 |
| Hs 578T | HG-6-64-01 | 10.0 | uM | LJP6 | 3 | M01 | 72 | hr | 765 | 196 | 3124 | 0.0627 | -0.2412 |
| Hs 578T | LDN-193189 | 10.0 | uM | LJP5 | 3 | G01 | 72 | hr | 765 | 197 | 3124 | 0.0630 | -0.2408 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1694 | 197 | 11155 | 0.0177 | -0.1583 |
| Hs 578T | HG-6-64-01 | 10.0 | uM | LJP6 | 2 | M01 | 72 | hr | 765 | 205 | 3124 | 0.0656 | -0.2374 |
| MCF 10A | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 1694 | 205 | 11155 | 0.0184 | -0.1574 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP6 | 2 | G01 | 72 | hr | 765 | 209 | 3124 | 0.0669 | -0.2357 |
| Hs 578T | Canertinib | 10.0 | uM | LJP6 | 1 | H07 | 72 | hr | 765 | 214 | 3124 | 0.0685 | -0.2336 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1694 | 215 | 11155 | 0.0193 | -0.1564 |
| Hs 578T | LDN-193189 | 10.0 | uM | LJP5 | 1 | G01 | 72 | hr | 765 | 218 | 3124 | 0.0698 | -0.2319 |