LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1389 | 1281 | 5667 | 0.2260 | -0.0253 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1389 | 3722 | 5667 | 0.6567 | 0.5452 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1694 | 2302 | 11155 | 0.2064 | 0.0642 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1389 | 895 | 5667 | 0.1579 | -0.1155 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1389 | 1185 | 5667 | 0.2091 | -0.0477 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1389 | 3343 | 5667 | 0.5898 | 0.4567 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1694 | 2548 | 11155 | 0.2284 | 0.0902 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1694 | 2272 | 11155 | 0.2037 | 0.0611 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1694 | 9936 | 11155 | 0.8907 | 0.8711 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1694 | 9851 | 11155 | 0.8831 | 0.8621 |
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 765 | 2609 | 3124 | 0.8350 | 0.7815 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 765 | 486 | 3124 | 0.1555 | -0.1183 |
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 765 | 2654 | 3124 | 0.8494 | 0.8006 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 1334 | 2407 | 3970 | 0.6062 | 0.4068 |
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 765 | 2678 | 3124 | 0.8571 | 0.8108 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 765 | 660 | 3124 | 0.2112 | -0.0445 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1334 | 3149 | 3970 | 0.7930 | 0.6882 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1334 | 2474 | 3970 | 0.6230 | 0.4322 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1334 | 987 | 3970 | 0.2486 | -0.1319 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1334 | 1020 | 3970 | 0.2569 | -0.1194 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1334 | 1149 | 3970 | 0.2894 | -0.0704 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 1694 | 10978 | 11155 | 0.9841 | 0.9812 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 765 | 386 | 3124 | 0.1235 | -0.1607 |
| MDA-MB-231 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1311 | 1780 | 5013 | 0.3550 | 0.1265 |
| MDA-MB-231 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1311 | 1395 | 5013 | 0.2783 | 0.0225 |