Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | 1 | b-NGF | 74.0 | 37 | |||||||
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | b-NGF | 62.0 | 61 | |
| RA2159 | IKK16 | 2.0 | uM | 1 | b-NGF | 40.0 | 53 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | b-NGF | 72.0 | 41 | ||||
| RA2159 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | b-NGF | 188.0 | 69 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | b-NGF | 201.5 | 56 | |
| RA2159 | PD184352 | 0.1 | uM | 1 | b-NGF | 53.5 | 68 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | 1 | b-NGF | 49.5 | 54 | ||||
| N2586 | PD184352 | 0.1 | uM | 1 | b-NGF | 113.0 | 71 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | b-NGF | 94.5 | 38 | ||||
| 0 | b-NGF | 11.0 | 40 | ||||||||
| RA2159 | TNF-a | 100 | ng/mL | 1 | b-NGF | 168.5 | 58 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | b-NGF | 126.0 | 75 | |
| RA2159 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | b-NGF | 159.0 | 62 | |
| 0 | b-NGF | 10.0 | 50 | ||||||||
| RA2159 | 1 | b-NGF | 41.0 | 59 | |||||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | b-NGF | 38.0 | 66 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | 1 | b-NGF | 49.0 | 57 | ||||
| RA2159 | 1 | b-NGF | 49.0 | 82 | |||||||
| N2586 | 1 | b-NGF | 92.0 | 71 | |||||||
| N2586 | Lestaurtinib | 0.3 | uM | 1 | b-NGF | 90.0 | 69 | ||||
| N2586 | Ruxolitinib | 0.3 | uM | 1 | b-NGF | 114.0 | 55 | ||||
| 0 | b-NGF | 8.5 | 58 | ||||||||
| N2586 | TNF-a | 100 | ng/mL | 1 | b-NGF | 358.0 | 33 | ||||
| RA2159 | EO1428 | 1.0 | uM | 1 | b-NGF | 46.0 | 44 |