Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 76.0 | 55 | |
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | MIP-1B | 60.5 | 60 | |
| N2586 | EO1428 | 1.0 | uM | 1 | MIP-1B | 78.5 | 38 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 180.0 | 73 | |
| N2586 | TNF-a | 100 | ng/mL | 1 | MIP-1B | 89.5 | 66 | ||||
| N2586 | IL-6 | 100 | ug/mL | 1 | MIP-1B | 75.5 | 76 | ||||
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 90.5 | 56 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 78.0 | 53 | |
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 171.5 | 52 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 167.0 | 47 | |
| N2586 | PI103 | 0.1 | uM | 1 | MIP-1B | 71.0 | 63 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | MIP-1B | 70.0 | 91 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | MIP-1B | 62.0 | 37 | ||||
| N2586 | 1 | MIP-1B | 72.0 | 42 | |||||||
| N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 96.5 | 62 | |
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 85.0 | 61 | |
| N2586 | 1 | MIP-1B | 69.0 | 66 | |||||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1B | 93.0 | 45 | |
| N2586 | PD184352 | 0.1 | uM | 1 | MIP-1B | 67.0 | 64 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 128.0 | 68 | ||||
| N2586 | Lestaurtinib | 0.3 | uM | 1 | MIP-1B | 74.0 | 56 | ||||
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1B | 80.0 | 73 | |
| N2586 | Ruxolitinib | 0.3 | uM | 1 | MIP-1B | 71.0 | 64 | ||||
| N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | MIP-1B | 70.0 | 55 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | MIP-1B | 73.0 | 65 |