PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| C32 | 5 | hr | p-p70S6K(T389) | NaN | NaN |
| C32 | 5 | hr | p-S6(S235/236) | 3.07550 | -0.63138 |
| C32 | 5 | hr | p-AMPK(T172) | -1.86480 | 0.11278 |
| C32 | 5 | hr | p-JNK(T183/Y185) | -0.87770 | -1.21210 |
| C32 | 5 | hr | Total c-Jun | 4.28680 | -0.87148 |
| C32 | 5 | hr | p-cJun(S63) | NaN | NaN |
| C32 | 5 | hr | p-P38(T180/Y182) | -0.57949 | 1.41810 |
| C32 | 5 | hr | p-HSP27(S82) | NaN | NaN |
| C32 | 5 | hr | p-NFKB(S536) | 2.29440 | 0.20441 |
| C32 | 5 | hr | Bim | -2.63110 | -0.01033 |
| C32 | 5 | hr | cPARP | 0.52546 | -0.38647 |
| C32 | 5 | hr | p-Histone H3(S10) | -1.29620 | 0.23172 |
| C32 | 5 | hr | p27 Kip1 | -1.15200 | 0.24865 |
| C32 | 10 | hr | p-p90RSK(S380) | NaN | NaN |
| C32 | 10 | hr | p-p90RSK(T573) | -1.31020 | -0.00316 |
| C32 | 10 | hr | p-AKT(T308) | -2.62680 | 0.88985 |
| C32 | 10 | hr | p-AKT(S473) | -3.92050 | 1.35650 |
| C32 | 10 | hr | p-mTOR(S2448) | NaN | NaN |
| C32 | 10 | hr | p-p70S6K(T421/S424) | 1.95890 | -0.31223 |
| C32 | 10 | hr | p-p70S6K(T389) | NaN | NaN |
| C32 | 10 | hr | p-S6(S235/236) | 3.84100 | -0.76963 |
| C32 | 10 | hr | p-AMPK(T172) | -1.34300 | 0.31521 |
| C32 | 10 | hr | p-JNK(T183/Y185) | -0.14121 | -1.12140 |
| C32 | 10 | hr | Total c-Jun | 6.72650 | -0.50940 |
| C32 | 10 | hr | p-cJun(S63) | NaN | NaN |