PCI-32765 KiNativ -- single dose experiment - Dataset (ID:20206)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
Ibrutinib Ramos (RA 1) LOK
DLKAGNVLMTLEGDIR
Lys2
-60.1
 1
uM
Ibrutinib Ramos (RA 1) KPCI
DLKLDNVLLDSEGHIK
Lys2
19.2
 1
uM
Ibrutinib Ramos (RA 1) BARK1
DLKPANILLDEHGHVR
Lys2
-1.0
 1
uM
Ibrutinib Ramos (RA 1) CDK11,CDK8
DLKPANILVMGEGPER
Lys2
-51.4
 1
uM
Ibrutinib Ramos (RA 1) MAST3
DLKPDNLLITSLGHIK
Lys2
-9.7
 1
uM
Ibrutinib Ramos (RA 1) RSK1 domain1
DLKPENILLDEEGHIKLTDFGLSKEAIDHEK
Lys2
-36.9
 1
uM
Ibrutinib Ramos (RA 1) RSK2 domain1
DLKPENILLDEEGHIKLTDFGLSKESIDHEK
Lys2
-17.1
 1
uM
Ibrutinib Ramos (RA 1) KS6B1
DLKPENIMLNHQGHVK
Lys2
-47.3
 1
uM
Ibrutinib Ramos (RA 1) CaMK2a,CaMK2b,CaMK2d,CaMK2g
DLKPENLLLASK
Lys2
-8.8
 1
uM
Ibrutinib Ramos (RA 1) KCC4
DLKPENLLYATPAPDAPLK
Lys2
-3.0
 1
uM
Ibrutinib Ramos (RA 1) p38d,p38g
DLKPGNLAVNEDCELK
Lys2
-36.6
 1
uM
Ibrutinib Ramos (RA 1) CDK7
DLKPNNLLLDENGVLK
Lys2
7.9
 1
uM
Ibrutinib Ramos (RA 1) CDC2
DLKPQNLLIDDKGTIK
Lys2
16.6
 1
uM
Ibrutinib Ramos (RA 1) CDK5
DLKPQNLLINR
Lys2
-2.6
 1
uM
Ibrutinib Ramos (RA 1) CDK2
DLKPQNLLINTEGAIK
Lys2
-1.6
 1
uM
Ibrutinib Ramos (RA 1) PKR
DLKPSNIFLVDTK
Lys2
4.0
 1
uM
Ibrutinib Ramos (RA 1) RSK1_domain2
DLKPSNILYVDESGNPECLR
Lys2
-3.5
 1
uM
Ibrutinib Ramos (RA 1) RSK2_domain2
DLKPSNILYVDESGNPESIR
Lys2
14.1
 1
uM
Ibrutinib Ramos (RA 1) JNK1,JNK2,JNK3
DLKPSNIVVK
Lys2
-3.3
 1
uM
Ibrutinib Ramos (RA 1) MK03
DLKPSNLLINTTCDLK
Lys2
-35.7
 1
uM
Ibrutinib Ramos (RA 1) MK01
DLKPSNLLLNTTCDLK
Lys2
21.5
 1
uM
Ibrutinib Ramos (RA 1) BRAF
DLKSNNIFLHEDLTVK
Lys2
31.0
 1
uM
Ibrutinib Ramos (RA 1) PITSLRE
DLKTSNLLLSHAGILK
Lys2
7.1
 1
uM
Ibrutinib Ramos (RA 1) NDR1
DTGHVYAMKILR
Lys1
-53.6
 1
uM
Ibrutinib Ramos (RA 1) PKD2
DVAVKVIDK
Lys1
13.2
 1
uM