PCI-32765 KiNativ -- single dose experiment - Dataset (ID:20206)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | Ramos (RA 1) | AMPKa1,AMPKa2 | VAVKILNR | Lys1 | 8.3 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MST4,YSK1 | DIKAANVLLSEQGDVK | Lys2 | -8.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | PIK3CB | VFGEDSVGVIFKNGDDLR | ATP | 8.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -87.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MAP2K1,MAP2K2 | DVKPSNILVNSR | Lys2 | -8.8 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CaMK2a,CaMK2b,CaMK2d,CaMK2g | DLKPENLLLASK | Lys2 | -8.8 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | GSK3B | DIKPQNLLLDPDTAVLK | Lys2 | 8.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | >90 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MP2K7 | DVKPSNILLDER | Lys2 | 9.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MASTL | LYAVKVVK | Lys1 | 9.3 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MAP3K5 | DIKGDNVLINTYSGVLK | Lys2 | -9.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | IKKE | SGELVAVKVFNTTSYLRPR | Lys1 | 9.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BTK | GQYDVAIKMIK | Lys1 | >97 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MAST3 | DLKPDNLLITSLGHIK | Lys2 | -9.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 98.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | >99 | 1 | uM |