TG-101348 KINOMEscan - Dataset (ID:20174)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Fedratinib | GAK | 1.1 | nM |
| Fedratinib | JAK2(JH1domain-catalytic) | 1.1 | nM |
| Fedratinib | DAPK3 | 1.2 | nM |
| Fedratinib | FLT3(D835H) | 4.9 | nM |
| Fedratinib | FLT3(D835Y) | 6.4 | nM |
| Fedratinib | STK16 | 6.6 | nM |
| Fedratinib | FLT3(K663Q) | 13.0 | nM |
| Fedratinib | DCAMKL3 | 13.0 | nM |
| Fedratinib | FLT3 | 13.0 | nM |
| Fedratinib | FLT3(ITD) | 16.0 | nM |
| Fedratinib | DAPK1 | 16.0 | nM |
| Fedratinib | JAK1(JH1domain-catalytic) | 18.0 | nM |
| Fedratinib | YSK4 | 19.0 | nM |
| Fedratinib | FLT3(N841I) | 20.0 | nM |
| Fedratinib | TYK2(JH1domain-catalytic) | 21.0 | nM |
| Fedratinib | DAPK2 | 29.0 | nM |
| Fedratinib | FLT3(R834Q) | 29.0 | nM |
| Fedratinib | BIKE | 32.0 | nM |
| Fedratinib | NUAK1 | 34.0 | nM |
| Fedratinib | AAK1 | 35.0 | nM |
| Fedratinib | FYN | 38.0 | nM |
| Fedratinib | SIK1 | 39.0 | nM |
| Fedratinib | ABL1(E255K)-phosphorylated | 40.0 | nM |
| Fedratinib | FAK1 | 42.0 | nM |
| Fedratinib | ABL1-phosphorylated | 44.0 | nM |