AMG-706 KINOMEscan - Dataset (ID:20150)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Motesanib | FLT3(D835Y) | 9500.0 | nM |
| Motesanib | RIPK2 | 9300.0 | nM |
| Motesanib | HCK | 8600.0 | nM |
| Motesanib | ABL1(F317L)-phosphorylated | 7700.0 | nM |
| Motesanib | EGFR(L858R) | 7100.0 | nM |
| Motesanib | FGR | 6900.0 | nM |
| Motesanib | M3K2 | 6900.0 | nM |
| Motesanib | FGFR4 | 6800.0 | nM |
| Motesanib | ABL1-phosphorylated | 6700.0 | nM |
| Motesanib | FGFR1 | 6200.0 | nM |
| Motesanib | MAP4K4 | 5800.0 | nM |
| Motesanib | STK35 | 5400.0 | nM |
| Motesanib | JAK1(JH1domain-catalytic) | 5200.0 | nM |
| Motesanib | YES | 5000.0 | nM |
| Motesanib | ABL1(Y253F)-phosphorylated | 4500.0 | nM |
| Motesanib | FLT3(D835H) | 4500.0 | nM |
| Motesanib | EGFR(L747-S752del, P753S) | 4500.0 | nM |
| Motesanib | ABL2 | 4500.0 | nM |
| Motesanib | GCN2(Kin.Dom.2,S808G) | 4400.0 | nM |
| Motesanib | ABL1(F317I)-nonphosphorylated | 4000.0 | nM |
| Motesanib | EGFR(L861Q) | 3900.0 | nM |
| Motesanib | FLT3(R834Q) | 3800.0 | nM |
| Motesanib | EGFR(E746-A750del) | 3800.0 | nM |
| Motesanib | FYN | 2800.0 | nM |
| Motesanib | EGFR(L747-T751del,Sins) | 2600.0 | nM |