Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
T47D | 0.000537 | 0.031946 | 0.009859 | 0.035689 | 0.027587 | 0.000443 | 0.002633 | 0.023322 | 0.017964 | 0.000220 | 0.000001 | 0.000193 | 0.000178 | 0.000267 | 0.000084 | 0.000000 | 0.001839 | 0.284085 | 0.000002 | 0.196300 | 0.001170 | 0.000018 | 0.000001 | 0.166496 | 0.000225 | 0.000704 | 0.184693 | 0.003680 | 0.011140 | 0.000052 | 0.004440 | 0.005092 | 0.006041 | 0.026736 | 0.000037 | 0.000013 | 0.000080 | 0.001178 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000127 | 0.000116 | 0.001290 | 0.019619 |
HCC1187 | 0.001231 | 0.067625 | 0.078729 | 0.041583 | 0.003479 | 0.000015 | 0.011093 | 0.000584 | 0.052908 | 0.000770 | 0.001859 | 0.000193 | 0.000393 | 0.000289 | 0.000084 | 0.018901 | 0.003747 | 0.287014 | 0.000002 | 0.279688 | 0.000459 | 0.000018 | 0.000001 | 0.158536 | 0.000156 | 0.000638 | 0.249109 | 0.010311 | 0.015487 | 0.000052 | 0.001503 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.011705 | 0.000080 | 0.001174 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000065 | 0.000116 | 0.000059 | 0.000147 |
BT-549 | 0.001734 | 0.028424 | 0.139275 | 0.011181 | 0.000070 | 0.000015 | 0.000061 | 0.005810 | 0.076807 | 0.000499 | 0.000001 | 0.000193 | 0.000497 | 0.000150 | 0.302179 | 0.000000 | 0.286646 | 0.294228 | 0.000002 | 0.294733 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000476 | 0.002044 | 0.303062 | 0.016341 | 0.012222 | 0.000052 | 0.014529 | 0.007478 | 0.005798 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.004543 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000203 | 0.000116 | 0.000041 | 0.000118 |
MDA-MB-175-VII | 0.001428 | 0.047847 | 0.007853 | 0.074796 | 0.009289 | 0.000015 | 0.000061 | 0.007339 | 0.012638 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.014355 | 0.340263 | 0.000002 | 0.243260 | 0.000002 | 0.000018 | 0.000001 | 0.044485 | 0.000851 | 0.008435 | 0.296530 | 0.000541 | 0.015937 | 0.009106 | 0.008008 | 0.006831 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000375 | 0.000116 | 0.000090 | 0.000047 |
MCF 10A | 0.000421 | 0.025576 | 0.132898 | 0.017434 | 0.001298 | 0.000015 | 0.000061 | 0.098369 | 0.025642 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.234945 | 0.000000 | 0.017445 | 0.342839 | 0.000002 | 0.157427 | 0.000002 | 0.000326 | 0.000001 | 0.009659 | 0.000027 | 0.000704 | 0.096342 | 0.020160 | 0.008104 | 0.000052 | 0.009461 | 0.034734 | 0.006760 | 0.035226 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000150 | 0.000116 | 0.000017 | 0.000054 |
HCC1500 | 0.001627 | 0.030076 | 0.008530 | 0.028522 | 0.021393 | 0.000533 | 0.013918 | 0.024088 | 0.044645 | 0.000527 | 0.000001 | 0.000193 | 0.000178 | 0.000462 | 0.000084 | 0.000000 | 0.000026 | 0.394097 | 0.000002 | 0.206517 | 0.003372 | 0.000565 | 0.000309 | 0.125318 | 0.000242 | 0.000234 | 0.004047 | 0.007146 | 0.010088 | 0.000052 | 0.002743 | 0.035367 | 0.002356 | 0.038419 | 0.000037 | 0.000013 | 0.000080 | 0.001452 | 0.000134 | 0.009774 | 0.001249 | 0.000023 | 0.000149 | 0.000895 | 0.004777 | 0.001929 |
ZR-75-1 | 0.002113 | 0.103132 | 0.002349 | 0.059202 | 0.026874 | 0.000015 | 0.000061 | 0.012358 | 0.009299 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.003798 | 0.401987 | 0.000002 | 0.168463 | 0.000316 | 0.000203 | 0.000485 | 0.260343 | 0.000085 | 0.000293 | 0.037924 | 0.001668 | 0.005695 | 0.000052 | 0.000027 | 0.003005 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002378 | 0.000134 | 0.000016 | 0.001249 | 0.000182 | 0.000155 | 0.000116 | 0.001157 | 0.006319 |
BT-20 | 0.000448 | 0.019443 | 0.425506 | 0.032790 | 0.007417 | 0.000015 | 0.000823 | 0.029500 | 0.003761 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.194375 | 0.000000 | 0.003806 | 0.656693 | 0.000002 | 0.132703 | 0.000002 | 0.000018 | 0.000001 | 0.337435 | 0.000112 | 0.000428 | 0.204619 | 0.194717 | 0.011525 | 0.000052 | 0.003270 | 0.005037 | 0.000037 | 0.009023 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.006500 | 0.001249 | 0.000023 | 0.000273 | 0.000116 | 0.000026 | 0.000062 |
184B5 | 0.000454 | 0.014484 | 0.199552 | 0.017611 | 0.002111 | 0.000015 | 0.001482 | 0.024421 | 0.024712 | 0.000108 | 0.001064 | 0.000193 | 0.000341 | 0.000006 | 0.421684 | 0.000000 | 0.022577 | 0.728929 | 0.000002 | 0.131405 | 0.000002 | 0.000018 | 0.000001 | 0.043860 | 0.000121 | 0.000989 | 0.064621 | 0.073694 | 0.004421 | 0.000052 | 0.001946 | 0.075541 | 0.018317 | 0.028019 | 0.000037 | 0.000013 | 0.000080 | 0.001258 | 0.000134 | 0.000879 | 0.001249 | 0.000023 | 0.000471 | 0.000430 | 0.000013 | 0.000061 |
UACC-812 | 0.002318 | 0.062712 | 0.003552 | 1.079578 | 0.011629 | 0.000015 | 0.000061 | 0.020988 | 0.030159 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.215155 | 0.000000 | 0.017181 | 1.395831 | 0.000002 | 0.292940 | 0.000132 | 0.000018 | 0.000001 | 0.268856 | 0.001274 | 0.006187 | 0.206463 | 0.016533 | 0.595025 | 0.000052 | 0.015995 | 0.000016 | 0.000037 | 0.109902 | 0.000037 | 0.000013 | 0.002079 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000628 | 0.000116 | 0.000341 | 0.000552 |
HCC1569 | 0.001239 | 0.025774 | 0.008103 | 1.209554 | 0.023939 | 0.000015 | 0.000061 | 0.063655 | 0.021025 | 0.000193 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.042288 | 0.000000 | 0.011558 | 1.525413 | 0.000002 | 0.217837 | 0.000745 | 0.000988 | 0.000001 | 0.107529 | 0.000572 | 0.000384 | 0.376618 | 0.014228 | 0.468610 | 0.000647 | 0.003379 | 0.003545 | 0.005121 | 0.001832 | 0.000037 | 0.000013 | 0.000399 | 0.000009 | 0.000134 | 0.002549 | 0.001249 | 0.000023 | 0.000337 | 0.000116 | 0.000060 | 0.000253 |
HCC1428 | 0.001057 | 0.075777 | 0.039530 | 0.038714 | 0.033628 | 0.001203 | 0.000061 | 0.024890 | 0.019215 | 0.000421 | 0.000001 | 0.000193 | 0.000178 | 0.000266 | 0.000084 | 0.000000 | 0.000837 | 1.543919 | 0.000002 | 0.176235 | 0.000002 | 0.000018 | 0.005277 | 0.166874 | 0.000109 | 0.000209 | 0.003641 | 0.014974 | 0.002229 | 0.000052 | 0.004321 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.004061 | 0.000080 | 0.000009 | 0.000134 | 0.003332 | 0.001249 | 0.000023 | 0.002004 | 0.000116 | 0.002332 | 0.001020 |
MDA-MB-415 | 0.002446 | 0.033470 | 0.000084 | 0.052998 | 0.031361 | 0.000015 | 0.002611 | 0.004987 | 0.015992 | 0.000647 | 0.000001 | 0.000193 | 0.000178 | 0.000332 | 0.008883 | 0.004072 | 0.008449 | 3.594383 | 0.000002 | 0.231456 | 0.001831 | 0.000338 | 0.003574 | 0.522981 | 0.000027 | 0.000863 | 1.048483 | 0.003479 | 0.010413 | 0.000052 | 0.003052 | 0.038631 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002433 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000360 | 0.000116 | 0.000496 | 0.000401 |
BT-483 | 0.001683 | 0.039293 | 0.001949 | 0.201151 | 0.092377 | 0.000015 | 0.007435 | 0.095137 | 0.014937 | 0.000720 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.000026 | 4.809215 | 0.000002 | 0.326895 | 0.000002 | 0.000018 | 0.016574 | 0.419402 | 0.000027 | 0.000627 | 0.121213 | 0.003177 | 0.020875 | 0.000052 | 0.004336 | 0.058032 | 0.108322 | 0.075505 | 0.000037 | 0.000013 | 0.000080 | 0.002872 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.002324 | 0.000116 | 0.001073 | 0.000638 |