Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-134-VI | 0.001427 | 0.021843 | 0.001077 | 0.012026 | 0.017004 | 0.000015 | 0.000061 | 0.022199 | 0.017814 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000361 | 0.000084 | 0.000000 | 0.000832 | 0.130079 | 0.000002 | 0.183013 | 0.000002 | 0.000018 | 0.000001 | 0.106023 | 0.000072 | 0.002491 | 0.001641 | 0.000014 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.001384 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000077 | 0.000116 | 0.001584 | 0.000079 |
MDA-MB-175-VII | 0.001428 | 0.047847 | 0.007853 | 0.074796 | 0.009289 | 0.000015 | 0.000061 | 0.007339 | 0.012638 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.014355 | 0.340263 | 0.000002 | 0.243260 | 0.000002 | 0.000018 | 0.000001 | 0.044485 | 0.000851 | 0.008435 | 0.296530 | 0.000541 | 0.015937 | 0.009106 | 0.008008 | 0.006831 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000375 | 0.000116 | 0.000090 | 0.000047 |
MDA-MB-231 | 0.000398 | 0.036028 | 0.083694 | 0.007956 | 0.000596 | 0.000015 | 0.000061 | 0.004737 | 0.031148 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.006061 | 0.080205 | 0.000000 | 0.117453 | 0.225337 | 0.000002 | 0.145332 | 0.000002 | 0.000018 | 0.000001 | 0.011123 | 0.000240 | 0.000712 | 0.006677 | 0.009967 | 0.003507 | 0.000052 | 0.001369 | 0.004480 | 0.000037 | 0.011474 | 0.000037 | 0.000013 | 0.000080 | 0.000578 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000116 | 0.000116 | 0.000025 | 0.000067 |
MDA-MB-361 | 0.001199 | 0.067506 | 0.001650 | 0.209101 | 0.014416 | 0.000015 | 0.003542 | 0.015756 | 0.016276 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.001031 | 0.100950 | 0.000002 | 0.126329 | 0.001094 | 0.000018 | 0.000001 | 0.283766 | 0.000027 | 0.000755 | 0.056652 | 0.005513 | 0.076155 | 0.000052 | 0.000802 | 0.014004 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000705 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000106 | 0.000116 | 0.001168 | 0.001303 |
MDA-MB-415 | 0.002446 | 0.033470 | 0.000084 | 0.052998 | 0.031361 | 0.000015 | 0.002611 | 0.004987 | 0.015992 | 0.000647 | 0.000001 | 0.000193 | 0.000178 | 0.000332 | 0.008883 | 0.004072 | 0.008449 | 3.594383 | 0.000002 | 0.231456 | 0.001831 | 0.000338 | 0.003574 | 0.522981 | 0.000027 | 0.000863 | 1.048483 | 0.003479 | 0.010413 | 0.000052 | 0.003052 | 0.038631 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002433 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000360 | 0.000116 | 0.000496 | 0.000401 |
MDA-MB-436 | 0.000792 | 0.015135 | 0.029664 | 0.002771 | 0.000755 | 0.000015 | 0.000061 | 0.009875 | 0.043402 | 0.000434 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.261698 | 0.000000 | 0.074511 | 0.038248 | 0.000002 | 0.161437 | 0.000002 | 0.000018 | 0.000001 | 0.004527 | 0.000187 | 0.001376 | 0.289644 | 0.001623 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000006 | 0.000046 |
MDA-MB-157 | 0.001092 | 0.054440 | 0.034858 | 0.006675 | 0.000070 | 0.000015 | 0.002708 | 0.001602 | 0.016440 | 0.000834 | 0.000001 | 0.000193 | 0.000320 | 0.110015 | 0.000084 | 0.008668 | 0.074062 | 0.088522 | 0.000002 | 0.158241 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000868 | 0.008996 | 0.002269 | 0.002229 | 0.000052 | 0.001407 | 0.006897 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000058 | 0.000116 | 0.000019 | 0.000130 |
184B5 | 0.000454 | 0.014484 | 0.199552 | 0.017611 | 0.002111 | 0.000015 | 0.001482 | 0.024421 | 0.024712 | 0.000108 | 0.001064 | 0.000193 | 0.000341 | 0.000006 | 0.421684 | 0.000000 | 0.022577 | 0.728929 | 0.000002 | 0.131405 | 0.000002 | 0.000018 | 0.000001 | 0.043860 | 0.000121 | 0.000989 | 0.064621 | 0.073694 | 0.004421 | 0.000052 | 0.001946 | 0.075541 | 0.018317 | 0.028019 | 0.000037 | 0.000013 | 0.000080 | 0.001258 | 0.000134 | 0.000879 | 0.001249 | 0.000023 | 0.000471 | 0.000430 | 0.000013 | 0.000061 |
HCC1187 | 0.001231 | 0.067625 | 0.078729 | 0.041583 | 0.003479 | 0.000015 | 0.011093 | 0.000584 | 0.052908 | 0.000770 | 0.001859 | 0.000193 | 0.000393 | 0.000289 | 0.000084 | 0.018901 | 0.003747 | 0.287014 | 0.000002 | 0.279688 | 0.000459 | 0.000018 | 0.000001 | 0.158536 | 0.000156 | 0.000638 | 0.249109 | 0.010311 | 0.015487 | 0.000052 | 0.001503 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.011705 | 0.000080 | 0.001174 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000065 | 0.000116 | 0.000059 | 0.000147 |
BT-549 | 0.001734 | 0.028424 | 0.139275 | 0.011181 | 0.000070 | 0.000015 | 0.000061 | 0.005810 | 0.076807 | 0.000499 | 0.000001 | 0.000193 | 0.000497 | 0.000150 | 0.302179 | 0.000000 | 0.286646 | 0.294228 | 0.000002 | 0.294733 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000476 | 0.002044 | 0.303062 | 0.016341 | 0.012222 | 0.000052 | 0.014529 | 0.007478 | 0.005798 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.004543 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000203 | 0.000116 | 0.000041 | 0.000118 |
HCC70 | 0.001861 | 0.030250 | 0.187019 | 0.018492 | 0.008284 | 0.000015 | 0.000061 | 0.006480 | 0.008221 | 0.000007 | 0.000001 | 0.000193 | 0.000510 | 0.000006 | 0.081869 | 0.005246 | 0.010598 | 0.079143 | 0.000002 | 0.127848 | 0.000002 | 0.000018 | 0.000001 | 0.241041 | 0.000422 | 0.000287 | 0.287724 | 0.077648 | 0.002229 | 0.000052 | 0.001546 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000088 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000015 | 0.000067 |
ZR-75-30 | 0.000961 | 0.079347 | 0.000084 | 2.054386 | 0.048846 | 0.000015 | 0.000061 | 0.007411 | 0.017689 | 0.000007 | 0.000001 | 0.000193 | 0.000605 | 0.000006 | 0.000084 | 0.000000 | 0.003164 | 0.221002 | 0.000002 | 0.194097 | 0.000002 | 0.001923 | 0.000145 | 0.057962 | 0.002051 | 0.004394 | 0.348622 | 0.002119 | 0.992071 | 0.020984 | 0.010718 | 0.022800 | 0.006964 | 0.001832 | 0.000037 | 0.000013 | 0.002139 | 0.001049 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000072 | 0.000116 | 0.000927 | 0.000116 |
HCC1395 | 0.000674 | 0.040023 | 0.039355 | 0.003057 | 0.000070 | 0.000015 | 0.000061 | 0.001431 | 0.011892 | 0.000371 | 0.000001 | 0.000193 | 0.000798 | 0.000006 | 0.029478 | 0.000000 | 0.015589 | 0.122642 | 0.000002 | 0.172335 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.001426 | 0.353474 | 0.002759 | 0.002229 | 0.000052 | 0.000683 | 0.007266 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000158 | 0.000116 | 0.000006 | 0.000057 |
Hs 578T | 0.001051 | 0.038658 | 0.108751 | 0.011487 | 0.000070 | 0.000015 | 0.000061 | 0.005070 | 0.021411 | 0.000007 | 0.000001 | 0.000193 | 0.032878 | 0.130946 | 0.205973 | 0.000000 | 0.081158 | 0.086798 | 0.000002 | 0.163343 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000416 | 0.127930 | 0.007434 | 0.002229 | 0.000052 | 0.000027 | 0.036628 | 0.000037 | 0.010027 | 0.000037 | 0.000013 | 0.000080 | 0.004200 | 0.001565 | 0.000016 | 0.001249 | 0.000023 | 0.000076 | 0.000116 | 0.000006 | 0.000047 |