Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MCF12A | 0.000301 | 0.016529 | 0.189237 | 0.008829 | 0.001731 | 0.000015 | 0.000061 | 0.013479 | 0.009227 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.510546 | 0.000000 | 0.017256 | 0.092326 | 0.000002 | 0.100947 | 0.000002 | 0.000018 | 0.000001 | 0.058942 | 0.000027 | 0.000134 | 0.017063 | 0.195698 | 0.002618 | 0.000052 | 0.000724 | 0.015404 | 0.010887 | 0.050437 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.009245 | 0.001249 | 0.000110 | 0.000256 | 0.000116 | 0.000058 | 0.000021 |
MCF 10A | 0.000421 | 0.025576 | 0.132898 | 0.017434 | 0.001298 | 0.000015 | 0.000061 | 0.098369 | 0.025642 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.234945 | 0.000000 | 0.017445 | 0.342839 | 0.000002 | 0.157427 | 0.000002 | 0.000326 | 0.000001 | 0.009659 | 0.000027 | 0.000704 | 0.096342 | 0.020160 | 0.008104 | 0.000052 | 0.009461 | 0.034734 | 0.006760 | 0.035226 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000150 | 0.000116 | 0.000017 | 0.000054 |
HCC1419 | 0.002537 | 0.068227 | 0.000084 | 3.032945 | 0.042585 | 0.000015 | 0.000061 | 0.005494 | 0.038255 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000331 | 0.000084 | 0.000000 | 0.019854 | 0.013025 | 0.000002 | 0.182028 | 0.000002 | 0.000288 | 0.001468 | 0.337559 | 0.000627 | 0.004841 | 0.566139 | 0.086873 | 2.431691 | 0.157330 | 0.273441 | 0.089457 | 0.056446 | 0.001832 | 0.000037 | 0.001134 | 0.005877 | 0.013438 | 0.000134 | 0.005253 | 0.001249 | 0.001041 | 0.000012 | 0.001878 | 0.000192 | 0.000120 |
184B5 | 0.000454 | 0.014484 | 0.199552 | 0.017611 | 0.002111 | 0.000015 | 0.001482 | 0.024421 | 0.024712 | 0.000108 | 0.001064 | 0.000193 | 0.000341 | 0.000006 | 0.421684 | 0.000000 | 0.022577 | 0.728929 | 0.000002 | 0.131405 | 0.000002 | 0.000018 | 0.000001 | 0.043860 | 0.000121 | 0.000989 | 0.064621 | 0.073694 | 0.004421 | 0.000052 | 0.001946 | 0.075541 | 0.018317 | 0.028019 | 0.000037 | 0.000013 | 0.000080 | 0.001258 | 0.000134 | 0.000879 | 0.001249 | 0.000023 | 0.000471 | 0.000430 | 0.000013 | 0.000061 |
HCC1954 | 0.001529 | 0.029251 | 0.062116 | 2.028436 | 0.016195 | 0.000015 | 0.000061 | 0.007680 | 0.016718 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.630281 | 0.000079 | 0.027379 | 0.205159 | 0.000002 | 0.233839 | 0.000002 | 0.000018 | 0.000001 | 0.351399 | 0.000212 | 0.000950 | 0.678940 | 0.267708 | 0.854272 | 0.016644 | 0.017337 | 0.022861 | 0.004967 | 0.020476 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.007201 | 0.001249 | 0.000210 | 0.000225 | 0.000116 | 0.000019 | 0.000072 |
HCC202 | 0.002293 | 0.083788 | 0.066754 | 0.935180 | 0.020796 | 0.000015 | 0.007420 | 0.003045 | 0.013029 | 0.000474 | 0.000001 | 0.000193 | 0.000178 | 0.000346 | 0.000084 | 0.000000 | 0.037725 | 0.250326 | 0.000002 | 0.264042 | 0.004160 | 0.000355 | 0.000253 | 0.991954 | 0.000945 | 0.007669 | 0.437659 | 0.038539 | 0.193317 | 0.000052 | 0.009899 | 0.019944 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000188 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000134 | 0.000116 | 0.000077 | 0.000228 |
HCC1806 | 0.000318 | 0.011655 | 0.129893 | 0.013936 | 0.005507 | 0.000015 | 0.001566 | 0.005981 | 0.014474 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000155 | 0.265546 | 0.001230 | 0.040565 | 0.152646 | 0.000002 | 0.111444 | 0.000212 | 0.000517 | 0.000001 | 0.220721 | 0.000027 | 0.000424 | 0.006053 | 0.010389 | 0.004573 | 0.000052 | 0.001242 | 0.003796 | 0.001630 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000519 | 0.000134 | 0.002095 | 0.001249 | 0.000023 | 0.000077 | 0.000116 | 0.000029 | 0.000044 |
HCC38 | 0.001650 | 0.030563 | 0.040007 | 0.041302 | 0.024356 | 0.000015 | 0.001698 | 0.013109 | 0.015090 | 0.000145 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.011841 | 0.002042 | 0.072876 | 0.280569 | 0.000002 | 0.260344 | 0.001299 | 0.000018 | 0.000001 | 0.763470 | 0.000257 | 0.000854 | 0.077133 | 0.008259 | 0.008386 | 0.000052 | 0.005543 | 0.001929 | 0.005388 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000137 | 0.000116 | 0.000053 | 0.000133 |
MDA-MB-157 | 0.001092 | 0.054440 | 0.034858 | 0.006675 | 0.000070 | 0.000015 | 0.002708 | 0.001602 | 0.016440 | 0.000834 | 0.000001 | 0.000193 | 0.000320 | 0.110015 | 0.000084 | 0.008668 | 0.074062 | 0.088522 | 0.000002 | 0.158241 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000868 | 0.008996 | 0.002269 | 0.002229 | 0.000052 | 0.001407 | 0.006897 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000058 | 0.000116 | 0.000019 | 0.000130 |
MDA-MB-436 | 0.000792 | 0.015135 | 0.029664 | 0.002771 | 0.000755 | 0.000015 | 0.000061 | 0.009875 | 0.043402 | 0.000434 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.261698 | 0.000000 | 0.074511 | 0.038248 | 0.000002 | 0.161437 | 0.000002 | 0.000018 | 0.000001 | 0.004527 | 0.000187 | 0.001376 | 0.289644 | 0.001623 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000006 | 0.000046 |
Hs 578T | 0.001051 | 0.038658 | 0.108751 | 0.011487 | 0.000070 | 0.000015 | 0.000061 | 0.005070 | 0.021411 | 0.000007 | 0.000001 | 0.000193 | 0.032878 | 0.130946 | 0.205973 | 0.000000 | 0.081158 | 0.086798 | 0.000002 | 0.163343 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000416 | 0.127930 | 0.007434 | 0.002229 | 0.000052 | 0.000027 | 0.036628 | 0.000037 | 0.010027 | 0.000037 | 0.000013 | 0.000080 | 0.004200 | 0.001565 | 0.000016 | 0.001249 | 0.000023 | 0.000076 | 0.000116 | 0.000006 | 0.000047 |
MDA-MB-231 | 0.000398 | 0.036028 | 0.083694 | 0.007956 | 0.000596 | 0.000015 | 0.000061 | 0.004737 | 0.031148 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.006061 | 0.080205 | 0.000000 | 0.117453 | 0.225337 | 0.000002 | 0.145332 | 0.000002 | 0.000018 | 0.000001 | 0.011123 | 0.000240 | 0.000712 | 0.006677 | 0.009967 | 0.003507 | 0.000052 | 0.001369 | 0.004480 | 0.000037 | 0.011474 | 0.000037 | 0.000013 | 0.000080 | 0.000578 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000116 | 0.000116 | 0.000025 | 0.000067 |
HCC1937 | 0.001734 | 0.023106 | 0.126316 | 0.023936 | 0.002304 | 0.000015 | 0.002695 | 0.001929 | 0.009279 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.199776 | 0.000000 | 0.135122 | 0.133118 | 0.000002 | 0.225204 | 0.000308 | 0.000847 | 0.000001 | 0.524161 | 0.000027 | 0.002131 | 0.296125 | 0.005225 | 0.002229 | 0.000052 | 0.005032 | 0.029760 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000120 | 0.000116 | 0.000072 | 0.000120 |
BT-549 | 0.001734 | 0.028424 | 0.139275 | 0.011181 | 0.000070 | 0.000015 | 0.000061 | 0.005810 | 0.076807 | 0.000499 | 0.000001 | 0.000193 | 0.000497 | 0.000150 | 0.302179 | 0.000000 | 0.286646 | 0.294228 | 0.000002 | 0.294733 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000476 | 0.002044 | 0.303062 | 0.016341 | 0.012222 | 0.000052 | 0.014529 | 0.007478 | 0.005798 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.004543 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000203 | 0.000116 | 0.000041 | 0.000118 |