Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-415 | 0.002446 | 0.033470 | 0.000084 | 0.052998 | 0.031361 | 0.000015 | 0.002611 | 0.004987 | 0.015992 | 0.000647 | 0.000001 | 0.000193 | 0.000178 | 0.000332 | 0.008883 | 0.004072 | 0.008449 | 3.594383 | 0.000002 | 0.231456 | 0.001831 | 0.000338 | 0.003574 | 0.522981 | 0.000027 | 0.000863 | 1.048483 | 0.003479 | 0.010413 | 0.000052 | 0.003052 | 0.038631 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002433 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000360 | 0.000116 | 0.000496 | 0.000401 |
MDA-MB-436 | 0.000792 | 0.015135 | 0.029664 | 0.002771 | 0.000755 | 0.000015 | 0.000061 | 0.009875 | 0.043402 | 0.000434 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.261698 | 0.000000 | 0.074511 | 0.038248 | 0.000002 | 0.161437 | 0.000002 | 0.000018 | 0.000001 | 0.004527 | 0.000187 | 0.001376 | 0.289644 | 0.001623 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000006 | 0.000046 |
MDA-MB-453 | 0.001429 | 0.120120 | 0.002807 | 0.247025 | 0.028565 | 0.000015 | 0.005737 | 0.002220 | 0.011964 | 0.000480 | 0.000001 | 0.000193 | 0.000178 | 0.000130 | 0.000084 | 0.000028 | 0.001600 | 0.000100 | 0.000002 | 0.263671 | 0.001494 | 0.000018 | 0.065669 | 0.382461 | 0.000189 | 0.002063 | 0.506361 | 0.007798 | 0.095964 | 0.007578 | 0.009805 | 0.016826 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002579 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000023 | 0.000116 | 0.000059 | 0.000160 |
MDA-MB-468 | 0.000581 | 0.018362 | 0.896891 | 0.000084 | 0.003846 | 0.002097 | 0.006354 | 0.003904 | 0.006148 | 0.000257 | 0.000409 | 0.000193 | 0.000178 | 0.000246 | 0.175679 | 0.000140 | 0.008254 | 0.089507 | 0.000002 | 0.158480 | 0.000157 | 0.000018 | 0.000001 | 0.570714 | 0.000096 | 0.000599 | 0.270148 | 0.172730 | 0.005938 | 0.000052 | 0.004697 | 0.013372 | 0.002274 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.001538 | 0.000134 | 0.000316 | 0.001249 | 0.000023 | 0.000077 | 0.005793 | 0.000048 | 0.000109 |
SK-BR-3 | 0.001342 | 0.034698 | 0.048976 | 1.435347 | 0.020326 | 0.000015 | 0.006894 | 0.001849 | 0.022520 | 0.000393 | 0.000001 | 0.000193 | 0.000178 | 0.000148 | 0.012486 | 0.000000 | 0.007871 | 0.176013 | 0.000002 | 0.229318 | 0.001439 | 0.000018 | 0.000001 | 0.320775 | 0.000193 | 0.001075 | 0.260260 | 0.369062 | 1.193345 | 0.014139 | 0.050887 | 0.029773 | 0.004110 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.001633 | 0.000134 | 0.003998 | 0.001249 | 0.000023 | 0.000048 | 0.000116 | 0.000030 | 0.000125 |
T47D | 0.000537 | 0.031946 | 0.009859 | 0.035689 | 0.027587 | 0.000443 | 0.002633 | 0.023322 | 0.017964 | 0.000220 | 0.000001 | 0.000193 | 0.000178 | 0.000267 | 0.000084 | 0.000000 | 0.001839 | 0.284085 | 0.000002 | 0.196300 | 0.001170 | 0.000018 | 0.000001 | 0.166496 | 0.000225 | 0.000704 | 0.184693 | 0.003680 | 0.011140 | 0.000052 | 0.004440 | 0.005092 | 0.006041 | 0.026736 | 0.000037 | 0.000013 | 0.000080 | 0.001178 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000127 | 0.000116 | 0.001290 | 0.019619 |
ZR-75-1 | 0.002113 | 0.103132 | 0.002349 | 0.059202 | 0.026874 | 0.000015 | 0.000061 | 0.012358 | 0.009299 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.003798 | 0.401987 | 0.000002 | 0.168463 | 0.000316 | 0.000203 | 0.000485 | 0.260343 | 0.000085 | 0.000293 | 0.037924 | 0.001668 | 0.005695 | 0.000052 | 0.000027 | 0.003005 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002378 | 0.000134 | 0.000016 | 0.001249 | 0.000182 | 0.000155 | 0.000116 | 0.001157 | 0.006319 |
Hs 578T | 0.001051 | 0.038658 | 0.108751 | 0.011487 | 0.000070 | 0.000015 | 0.000061 | 0.005070 | 0.021411 | 0.000007 | 0.000001 | 0.000193 | 0.032878 | 0.130946 | 0.205973 | 0.000000 | 0.081158 | 0.086798 | 0.000002 | 0.163343 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000416 | 0.127930 | 0.007434 | 0.002229 | 0.000052 | 0.000027 | 0.036628 | 0.000037 | 0.010027 | 0.000037 | 0.000013 | 0.000080 | 0.004200 | 0.001565 | 0.000016 | 0.001249 | 0.000023 | 0.000076 | 0.000116 | 0.000006 | 0.000047 |
BT-20 | 0.000448 | 0.019443 | 0.425506 | 0.032790 | 0.007417 | 0.000015 | 0.000823 | 0.029500 | 0.003761 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.194375 | 0.000000 | 0.003806 | 0.656693 | 0.000002 | 0.132703 | 0.000002 | 0.000018 | 0.000001 | 0.337435 | 0.000112 | 0.000428 | 0.204619 | 0.194717 | 0.011525 | 0.000052 | 0.003270 | 0.005037 | 0.000037 | 0.009023 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.006500 | 0.001249 | 0.000023 | 0.000273 | 0.000116 | 0.000026 | 0.000062 |
BT-483 | 0.001683 | 0.039293 | 0.001949 | 0.201151 | 0.092377 | 0.000015 | 0.007435 | 0.095137 | 0.014937 | 0.000720 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.000026 | 4.809215 | 0.000002 | 0.326895 | 0.000002 | 0.000018 | 0.016574 | 0.419402 | 0.000027 | 0.000627 | 0.121213 | 0.003177 | 0.020875 | 0.000052 | 0.004336 | 0.058032 | 0.108322 | 0.075505 | 0.000037 | 0.000013 | 0.000080 | 0.002872 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.002324 | 0.000116 | 0.001073 | 0.000638 |
BT-549 | 0.001734 | 0.028424 | 0.139275 | 0.011181 | 0.000070 | 0.000015 | 0.000061 | 0.005810 | 0.076807 | 0.000499 | 0.000001 | 0.000193 | 0.000497 | 0.000150 | 0.302179 | 0.000000 | 0.286646 | 0.294228 | 0.000002 | 0.294733 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000476 | 0.002044 | 0.303062 | 0.016341 | 0.012222 | 0.000052 | 0.014529 | 0.007478 | 0.005798 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.004543 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000203 | 0.000116 | 0.000041 | 0.000118 |
CAMA-1 | 0.001036 | 0.016002 | 0.023685 | 0.063188 | 0.038498 | 0.002453 | 0.001774 | 0.005626 | 0.012643 | 0.000121 | 0.000001 | 0.000193 | 0.000178 | 0.000136 | 0.000084 | 0.000000 | 0.000750 | 0.057732 | 0.000002 | 0.126539 | 0.000002 | 0.000018 | 0.004167 | 0.073086 | 0.000027 | 0.000478 | 0.270453 | 0.000507 | 0.007421 | 0.000052 | 0.001415 | 0.019842 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000025 | 0.000116 | 0.001466 | 0.004511 |
HCC1187 | 0.001231 | 0.067625 | 0.078729 | 0.041583 | 0.003479 | 0.000015 | 0.011093 | 0.000584 | 0.052908 | 0.000770 | 0.001859 | 0.000193 | 0.000393 | 0.000289 | 0.000084 | 0.018901 | 0.003747 | 0.287014 | 0.000002 | 0.279688 | 0.000459 | 0.000018 | 0.000001 | 0.158536 | 0.000156 | 0.000638 | 0.249109 | 0.010311 | 0.015487 | 0.000052 | 0.001503 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.011705 | 0.000080 | 0.001174 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000065 | 0.000116 | 0.000059 | 0.000147 |
HCC1395 | 0.000674 | 0.040023 | 0.039355 | 0.003057 | 0.000070 | 0.000015 | 0.000061 | 0.001431 | 0.011892 | 0.000371 | 0.000001 | 0.000193 | 0.000798 | 0.000006 | 0.029478 | 0.000000 | 0.015589 | 0.122642 | 0.000002 | 0.172335 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.001426 | 0.353474 | 0.002759 | 0.002229 | 0.000052 | 0.000683 | 0.007266 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000158 | 0.000116 | 0.000006 | 0.000057 |