Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Omipalisib | BT-549 | -4.4776 | 0.9671 | -7.4066 | -7.1032 | -7.3547 | 0.7457 | 0.2033 | 0.2085 | 5.3689 |
| Omipalisib | CAMA-1 | -4.4776 | 0.9464 | -6.7651 | -6.7125 | -7.1194 | 1.3345 | 0.0749 | 0.0757 | 5.5519 |
| Omipalisib | HCC1143 | -4.4776 | 0.9819 | -7.3286 | -7.1069 | -7.4557 | 0.8936 | 0.1828 | 0.1851 | 5.2906 |
| Omipalisib | HCC1395 | -4.4776 | 0.9674 | -7.0311 | -6.6125 | -7.3086 | 0.9230 | 0.2903 | 0.2936 | 6.1517 |
| Omipalisib | HCC1419 | -4.4776 | 0.9393 | -7.8176 | -7.3177 | -8.7550 | 0.7216 | 0.2822 | 0.2850 | 5.2439 |
| Omipalisib | HCC1428 | -4.4776 | 0.9389 | -7.0436 | -6.6504 | -7.5424 | 0.8643 | 0.2607 | 0.2826 | 5.9711 |
| Omipalisib | HCC1569 | -4.4776 | 0.9648 | -7.7576 | -7.5276 | -7.7975 | 1.2645 | 0.2412 | 0.2413 | 5.1165 |
| Omipalisib | HCC1806 | -4.4776 | 0.9844 | -7.2646 | -7.1920 | -7.5727 | 0.6333 | 0.0504 | 0.0665 | 4.7285 |
| Omipalisib | HCC1937 | -4.4776 | 0.9796 | -7.3266 | -6.9723 | -7.5849 | 0.6869 | 0.2146 | 0.2232 | 5.4591 |
| Omipalisib | HCC1954 | -4.4776 | 0.9507 | -7.8256 | -7.7807 | -8.1463 | 1.1974 | 0.0450 | 0.0466 | 3.8101 |
| Omipalisib | HCC202 | -4.4776 | 0.9925 | -8.0786 | -8.0068 | -8.9423 | 0.9984 | 0.0758 | 0.0760 | 3.7918 |
| Omipalisib | HCC38 | -4.4776 | 0.9805 | -7.1526 | -7.0798 | -7.6187 | 0.9370 | 0.0549 | 0.0595 | 4.8099 |
| Omipalisib | HCC70 | -4.4776 | 0.9751 | -7.5826 | -7.5358 | -8.1178 | 0.8673 | 0.0444 | 0.0464 | 4.2358 |
| Omipalisib | Hs 578T | -4.4776 | 0.9865 | -7.1286 | -6.9171 | -7.1638 | 0.7774 | 0.1579 | 0.1652 | 6.6007 |
| Omipalisib | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Omipalisib | MDA-MB-134-VI | -4.4776 | 0.9885 | -7.2176 | -7.2177 | -7.9713 | 0.7442 | 0.0000 | 0.0092 | 4.4619 |
| Omipalisib | MDA-MB-157 | -4.4776 | 0.9549 | -6.0816 | -5.4106 | -6.5395 | 0.6444 | 0.2980 | 0.3850 | 6.9857 |
| Omipalisib | MDA-MB-175-VII | -4.4776 | 0.9651 | -7.4526 | -7.2379 | -8.2980 | 0.6747 | 0.1421 | 0.1505 | 4.9106 |
| Omipalisib | MDA-MB-361 | -4.4776 | 0.9850 | -7.9296 | -7.9292 | -8.7448 | 0.8961 | 0.0000 | 0.0012 | 3.5825 |
| Omipalisib | MDA-MB-436 | -4.4776 | 0.9036 | -6.8166 | -4.4776 | -6.3941 | 2.0130 | 0.6115 | 0.6115 | 7.4655 |
| Omipalisib | MDA-MB-453 | -4.4776 | 0.9438 | -7.6551 | -7.6413 | -8.4034 | 0.5528 | 0.0102 | 0.0332 | 3.9920 |
| Omipalisib | MDA-MB-468 | -4.4776 | 0.9771 | -7.1516 | -7.0505 | -7.5021 | 0.5801 | 0.0633 | 0.0889 | 4.9370 |
| Omipalisib | T47D | -4.4776 | 0.9689 | -8.1006 | -7.7796 | -8.4455 | 0.8613 | 0.2355 | 0.2361 | 4.7349 |
| Omipalisib | UACC-812 | -4.4776 | 0.9627 | -7.8116 | -7.4222 | -8.4852 | 0.7176 | 0.2361 | 0.2394 | 4.9312 |
| Omipalisib | UACC-893 | -4.4776 | 0.9805 | -7.5856 | -7.5235 | -8.0451 | 1.0350 | 0.0808 | 0.0810 | 4.3840 |