Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | Torin1 | 3 | 72 | 0.001 | 4036.8 | 4147.8 | 571.3 | -3.0 | 0.981 | 0.973 | 2.860 | Hs578T Torin1 3 |
| Hs 578T | Torin2 | 3 | 72 | 0.001 | 3608.8 | 4103.3 | 571.3 | -3.0 | 0.912 | 0.879 | 2.844 | Hs578T Torin2 3 |
| Hs 578T | Trametinib | 3 | 72 | 0.001 | 3280.0 | 4062.0 | 571.3 | -3.0 | 0.854 | 0.807 | 2.830 | Hs578T Trametinib 3 |
| Hs 578T | WYE-125132 | 3 | 72 | 0.001 | 3852.0 | 4195.3 | 571.3 | -3.0 | 0.942 | 0.918 | 2.876 | Hs578T WYE125132 3 |
| Hs 578T | XL147 | 3 | 72 | 0.001 | 4128.5 | 4203.0 | 571.3 | -3.0 | 0.988 | 0.982 | 2.879 | Hs578T XL147 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.001 | 4138.3 | 4157.8 | 571.3 | -3.0 | 0.997 | 0.995 | 2.863 | Hs578T ZSTK474 3 |