Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Buparlisib | 3 | 72 | 0.32 | 10585.3 | 11660.8 | 1273.3 | -0.495 | 0.940 | 0.908 | 3.195 | HCC1806 BKM120 0 3 72 |
| HCC1806 | Buparlisib | 3 | 72 | 1.0 | 3030.5 | 11660.8 | 1273.3 | 0.0 | 0.312 | 0.260 | 3.195 | HCC1806 BKM120 0 3 72 |
| HCC1806 | Buparlisib | 3 | 72 | 3.2 | 493.8 | 11660.8 | 1273.3 | 0.505 | -0.257 | 0.042 | 3.195 | HCC1806 BKM120 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 0.001 | 11136.3 | 11641.0 | 1273.3 | -3.0 | 0.972 | 0.957 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 0.0032 | 11758.0 | 11641.0 | 1273.3 | -2.49 | 1.010 | 1.010 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 0.01 | 11557.5 | 11641.0 | 1273.3 | -2.0 | 0.995 | 0.993 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 0.032 | 11715.5 | 11641.0 | 1273.3 | -1.49 | 1.000 | 1.010 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 0.1 | 11604.5 | 11641.0 | 1273.3 | -1.0 | 0.998 | 0.997 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 0.32 | 11016.8 | 11641.0 | 1273.3 | -0.495 | 0.966 | 0.946 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 1.0 | 5114.5 | 11641.0 | 1273.3 | 0.0 | 0.546 | 0.439 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | BX-912 | 3 | 72 | 3.2 | 2492.8 | 11641.0 | 1273.3 | 0.505 | 0.234 | 0.214 | 3.193 | HCC1806 BX912 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 0.001 | 10768.8 | 11894.0 | 1273.3 | -3.0 | 0.939 | 0.905 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 0.0032 | 10690.3 | 11894.0 | 1273.3 | -2.49 | 0.935 | 0.899 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 0.01 | 10822.0 | 11894.0 | 1273.3 | -2.0 | 0.942 | 0.910 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 0.032 | 11055.0 | 11894.0 | 1273.3 | -1.49 | 0.955 | 0.929 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 0.1 | 11102.8 | 11894.0 | 1273.3 | -1.0 | 0.958 | 0.933 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 0.32 | 11152.3 | 11894.0 | 1273.3 | -0.495 | 0.960 | 0.938 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 1.0 | 11213.0 | 11894.0 | 1273.3 | 0.0 | 0.964 | 0.943 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | Alpelisib | 3 | 72 | 3.2 | 10596.3 | 11894.0 | 1273.3 | 0.505 | 0.930 | 0.891 | 3.224 | HCC1806 BYL719 0 3 72 |
| HCC1806 | CAL-101 | 3 | 72 | 0.001 | 11230.8 | 11282.8 | 1273.3 | -3.0 | 0.997 | 0.995 | 3.147 | HCC1806 CAL101 0 3 72 |
| HCC1806 | CAL-101 | 3 | 72 | 0.0032 | 11273.8 | 11282.8 | 1273.3 | -2.49 | 0.999 | 0.999 | 3.147 | HCC1806 CAL101 0 3 72 |
| HCC1806 | CAL-101 | 3 | 72 | 0.01 | 11404.3 | 11282.8 | 1273.3 | -2.0 | 1.010 | 1.010 | 3.147 | HCC1806 CAL101 0 3 72 |
| HCC1806 | CAL-101 | 3 | 72 | 0.032 | 11305.3 | 11282.8 | 1273.3 | -1.49 | 1.000 | 1.000 | 3.147 | HCC1806 CAL101 0 3 72 |
| HCC1806 | CAL-101 | 3 | 72 | 0.1 | 11409.3 | 11282.8 | 1273.3 | -1.0 | 1.010 | 1.010 | 3.147 | HCC1806 CAL101 0 3 72 |
| HCC1806 | CAL-101 | 3 | 72 | 0.32 | 11440.8 | 11282.8 | 1273.3 | -0.495 | 1.010 | 1.010 | 3.147 | HCC1806 CAL101 0 3 72 |