LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)
Data Columns
Download: Excel (XLSX), Comma-separated (CSV)
- 11 Data Columns
| Name | Description | Display Name | Data Type | Unit | Precision | Readout Type | Replicate | Comments |
|---|---|---|---|---|---|---|---|---|
| cell | Cell reagent | Cell | Text | |||||
| smallMolecule | Small molecule perturbagen | Small Molecule | small_molecule | |||||
| timepoint | Timepoint | Numeric | 0 | |||||
| gR50 | Small molecule concentration in uM at which GR(c)=0.5 | GR50 | Numeric | 4 | ||||
| gRmax | Normalized growth inhibition rate at the highest tested concentration | GRmax | Numeric | 4 | ||||
| gRAOC | Integral of GR(c) over the range of concentrations tested | GR_AOC | Numeric | 4 | ||||
| gEC50 | Small molecule concentration in uM that results in 50% efficacy | GEC50 | Numeric | 5 | ||||
| gRinf | Effect of the drug at infinite concentration | GRinf | Numeric | 4 | ||||
| hGR | GR Hill Coefficient of the fitted curve | h_GR | Numeric | 4 | ||||
| r2GR | r^2 for the sigmoidal curve fit to the dose-response data | r2_GR | Numeric | 4 | ||||
| pvalGR | pval_GR | Text |
- 11 Data Columns