Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

 Full screen view
Filter results: >>>>
Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
Hs 578T HY-17541A 72
2.67034332565
 -0.5936 0.4776 3.6894 -0.5809 2.3850
Hs 578T HY-17542 72
inf
 0.9246 -0.0205 0.0000 1.0000 0.0100
Hs 578T HY-50736 72
0.206859851043
 -0.1514 0.8157 0.2773 -0.2770 1.5040
Hs 578T HY-50737A 72
1.00080504529
 -0.3945 0.5891 1.4659 -0.3655 1.4376
Hs 578T IU1 72
63.4449771188
 0.6256 0.0170 49.9183 0.2532 2.9451
Hs 578T LDN57444 72
19.4934085155
 -0.0884 0.1662 33.0205 -0.6495 1.5795
Hs 578T MI-2 72
1.32338090995
 -0.3256 0.5792 1.5805 -0.3890 3.2415
Hs 578T ML-323 72
133.678939825
 0.6153 0.1131 2077.0523 -1.0000 0.4005
Hs 578T Pevonedistat 72
0.250318851881
 -0.1834 0.6322 0.2775 -0.0801 1.4401
Hs 578T PB49673382 72
9.65679731349
 0.0485 0.1681 9.2758 0.0479 2.5005
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one 72
inf
 1.0210 0.0119 0.0000 0.9987 0.0100
Hs 578T SB1-F-21 72
0.452409395258
 -0.5167 0.7097 0.8042 -0.4961 1.1980
Hs 578T SB1-F-22 72
48.629206693
 0.4746 0.0557 108.1899 -1.0000 1.3738
Hs 578T SJB2-043 72
0.328943396017
 -0.5256 0.7088 0.4990 -0.5345 1.7452
Hs 578T SJB3-019A 72
0.213429884281
 -0.5583 0.9652 0.2838 -0.5792 2.6988
Hs 578T STK547622 72
inf
 0.9647 0.0155 0.0000 0.9968 0.0100
Hs 578T Vialinin A 72
5.33738832012
 -0.3425 0.2871 8.1284 -0.4124 1.4299
Hs 578T Degrasyn 72
1.34100869906
 -0.4283 0.6057 1.6245 -0.4514 3.3543
Hs 578T Sepantronium 72
0.111331714329
 -0.4992 0.9039 0.2765 -0.5106 0.7735
Hs 578T b-AP15 72
0.0926975330711
 -0.5434 1.0259 0.1069 -0.4418 4.4499
Hs 578T Doxycycline 72
inf
 1.3436 -0.0222 0.0000 1.0000 0.0100
Hs 578T Mitoxantrone 72
0.00035868699252
 -0.6845 1.3575 0.0152 -0.8850 0.2720
Hs 578T P22077 72
9.90749185438
 -0.5101 0.2336 15.3845 -0.6793 1.9498
Hs 578T Pimozide 72
11.1489853717
 -0.4944 0.2897 12.6490 -0.4399 5.0000
Hs 578T Spautin-1 72
inf
 0.7282 0.0530 11.0726 0.6652 1.0834