Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1937 | b-AP15 | 0.009992797 | 1.1087 | 0.00415 |
| HCC1937 | b-AP15 | 0.0316 | 1.0470 | -0.00970 |
| HCC1937 | b-AP15 | 0.099927974 | 0.7340 | 0.00181 |
| HCC1937 | b-AP15 | 0.316 | 0.0916 | 0.15569 |
| HCC1937 | b-AP15 | 0.999279741 | -0.4078 | 0.54269 |
| HCC1937 | b-AP15 | 3.16 | -0.3969 | 0.45595 |
| HCC1937 | b-AP15 | 9.992797406 | -0.5493 | 0.61849 |
| HCC1937 | b-AP15 | 31.6 | -0.5230 | 0.56007 |
| HCC1937 | b-AP15 | 50.0 | -0.5006 | 0.55607 |
| HCC1937 | USP7-IN-1 | 0.009992797 | 1.0118 | 0.00238 |
| HCC1937 | USP7-IN-1 | 0.0316 | 1.0545 | 0.00935 |
| HCC1937 | USP7-IN-1 | 0.099927974 | 1.0190 | -0.00623 |
| HCC1937 | USP7-IN-1 | 0.316 | 0.9951 | 0.00601 |
| HCC1937 | USP7-IN-1 | 0.999279741 | 1.0390 | -0.00186 |
| HCC1937 | USP7-IN-1 | 3.16 | 1.0141 | -0.00265 |
| HCC1937 | USP7-IN-1 | 9.992797406 | 0.9527 | -0.00306 |
| HCC1937 | USP7-IN-1 | 31.6 | 0.9723 | 0.00028 |
| HCC1937 | USP7-IN-1 | 50.0 | 0.8119 | 0.05130 |
| HCC1937 | Doxycycline | 0.009992797 | 0.8585 | 0.00741 |
| HCC1937 | Doxycycline | 0.0316 | 1.0898 | -0.00435 |
| HCC1937 | Doxycycline | 0.099927974 | 0.9877 | -0.00298 |
| HCC1937 | Doxycycline | 0.316 | 1.0830 | -0.00717 |
| HCC1937 | Doxycycline | 0.999279741 | 1.0262 | -0.00248 |
| HCC1937 | Doxycycline | 3.16 | 1.0431 | -0.00388 |
| HCC1937 | Doxycycline | 9.992797406 | 0.9314 | -0.00024 |