Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1428 | Sepantronium | 0.316 | -0.5946 | 0.65023 |
| HCC1428 | Sepantronium | 0.999279741 | -0.7157 | 0.72469 |
| HCC1428 | Sepantronium | 3.16 | -0.7548 | 0.73406 |
| HCC1428 | Sepantronium | 9.992797406 | -0.7710 | 0.75558 |
| HCC1428 | Sepantronium | 31.6 | -0.7607 | 0.73554 |
| HCC1428 | Sepantronium | 50.0 | -0.7576 | 0.53817 |
| HCC1428 | z-VAE(OMe)-fmk | 0.009992797 | 1.0454 | -0.00216 |
| HCC1428 | z-VAE(OMe)-fmk | 0.0316 | 0.9344 | -0.00788 |
| HCC1428 | z-VAE(OMe)-fmk | 0.099927974 | 1.0159 | -0.00385 |
| HCC1428 | z-VAE(OMe)-fmk | 0.316 | 0.8720 | -0.01714 |
| HCC1428 | z-VAE(OMe)-fmk | 0.999279741 | 0.9474 | -0.00678 |
| HCC1428 | z-VAE(OMe)-fmk | 3.16 | 0.8961 | -0.01243 |
| HCC1428 | z-VAE(OMe)-fmk | 9.992797406 | 0.8928 | 0.00224 |
| HCC1428 | z-VAE(OMe)-fmk | 31.6 | 0.9944 | -0.00028 |
| HCC1428 | z-VAE(OMe)-fmk | 50.0 | 1.0206 | 0.03331 |
| HCC1500 | 1247825-37-1 | 0.009992797 | 1.1362 | -0.00315 |
| HCC1500 | 1247825-37-1 | 0.0316 | 1.1297 | 0.01334 |
| HCC1500 | 1247825-37-1 | 0.099927974 | 0.9598 | 0.00892 |
| HCC1500 | 1247825-37-1 | 0.316 | 0.9626 | 0.01706 |
| HCC1500 | 1247825-37-1 | 0.999279741 | 0.9009 | 0.01914 |
| HCC1500 | 1247825-37-1 | 3.16 | 1.0244 | 0.05811 |
| HCC1500 | 1247825-37-1 | 9.992797406 | 0.3773 | 0.16885 |
| HCC1500 | 1247825-37-1 | 31.6 | -0.3609 | 0.52157 |
| HCC1500 | 1247825-37-1 | 50.0 | -0.3852 | 0.54552 |
| HCC1500 | b-AP15 | 0.009992797 | 1.1951 | 0.01774 |