Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1428 | MI-2 | 9.992797406 | -0.7545 | 0.72496 |
| HCC1428 | MI-2 | 31.6 | -0.7443 | 0.75058 |
| HCC1428 | MI-2 | 50.0 | -0.7986 | 0.57335 |
| HCC1428 | Mitoxantrone | 0.009992797 | 0.1247 | 0.04061 |
| HCC1428 | Mitoxantrone | 0.0316 | 0.1728 | 0.04284 |
| HCC1428 | Mitoxantrone | 0.099927974 | 0.0664 | 0.09676 |
| HCC1428 | Mitoxantrone | 0.316 | -0.0530 | 0.41806 |
| HCC1428 | Mitoxantrone | 0.999279741 | -0.5677 | 0.66987 |
| HCC1428 | Mitoxantrone | 3.16 | -0.7370 | 0.68670 |
| HCC1428 | Mitoxantrone | 9.992797406 | -0.7076 | 0.54922 |
| HCC1428 | Mitoxantrone | 31.6 | -0.6226 | 0.27803 |
| HCC1428 | Mitoxantrone | 50.0 | -0.2050 | 0.22893 |
| HCC1428 | ML-323 | 0.009992797 | 0.9871 | -0.00904 |
| HCC1428 | ML-323 | 0.0316 | 0.9731 | -0.00361 |
| HCC1428 | ML-323 | 0.099927974 | 1.1849 | 0.00732 |
| HCC1428 | ML-323 | 0.316 | 0.9360 | -0.00160 |
| HCC1428 | ML-323 | 0.999279741 | 0.8679 | -0.00597 |
| HCC1428 | ML-323 | 3.16 | 0.6702 | 0.01898 |
| HCC1428 | ML-323 | 9.992797406 | 0.8699 | 0.00061 |
| HCC1428 | ML-323 | 31.6 | 0.6697 | -0.00828 |
| HCC1428 | ML-323 | 50.0 | 0.5825 | 0.00075 |
| HCC1428 | Pevonedistat | 0.009992797 | 0.8763 | 0.01929 |
| HCC1428 | Pevonedistat | 0.0316 | 0.7750 | 0.05266 |
| HCC1428 | Pevonedistat | 0.099927974 | 0.1856 | 0.12117 |
| HCC1428 | Pevonedistat | 0.316 | -0.1508 | 0.18036 |