Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 1.0260 0.00116
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9816 -0.00575
HCC1419 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0639 0.00204
HCC1419 SB1-F-21
0.009992797
 0.9533 -0.00326
HCC1419 SB1-F-21
0.0316
 1.0535 0.00065
HCC1419 SB1-F-21
0.099927974
 1.0563 -0.00078
HCC1419 SB1-F-21
0.316
 0.9306 0.05492
HCC1419 SB1-F-21
0.999279741
 0.1263 0.29239
HCC1419 SB1-F-21
3.16
 -0.2050 0.45401
HCC1419 SB1-F-21
9.992797406
 -0.3007 0.45815
HCC1419 SB1-F-21
31.6
 -0.4674 0.54192
HCC1419 SB1-F-21
50.0
 -0.4335 0.37834
HCC1419 SB1-F-22
0.009992797
 1.0944 0.00187
HCC1419 SB1-F-22
0.0316
 1.0670 -0.00501
HCC1419 SB1-F-22
0.099927974
 1.0704 -0.00187
HCC1419 SB1-F-22
0.316
 0.9452 0.00059
HCC1419 SB1-F-22
0.999279741
 0.9430 -0.00318
HCC1419 SB1-F-22
3.16
 0.9039 0.00427
HCC1419 SB1-F-22
9.992797406
 0.7033 0.00809
HCC1419 SB1-F-22
31.6
 0.2855 0.03679
HCC1419 SB1-F-22
50.0
 0.4358 0.01815
HCC1419 SJB2-043
0.00316
 0.8831 -0.00304
HCC1419 SJB2-043
0.009992797
 1.0013 -0.00677
HCC1419 SJB2-043
0.0316
 1.0329 -0.00548
HCC1419 SJB2-043
0.099927974
 1.1343 0.00584