Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1419 | b-AP15 | 0.099927974 | 0.8533 | 0.00412 |
| HCC1419 | b-AP15 | 0.316 | 0.0687 | 0.13467 |
| HCC1419 | b-AP15 | 0.999279741 | -0.1236 | 0.23220 |
| HCC1419 | b-AP15 | 3.16 | -0.4509 | 0.46269 |
| HCC1419 | b-AP15 | 9.992797406 | -0.7407 | 0.77887 |
| HCC1419 | b-AP15 | 31.6 | -0.7204 | 0.76755 |
| HCC1419 | b-AP15 | 50.0 | -0.6960 | 0.75300 |
| HCC1419 | USP7-IN-1 | 0.009992797 | 1.0411 | 0.00184 |
| HCC1419 | USP7-IN-1 | 0.0316 | 1.0546 | 0.00041 |
| HCC1419 | USP7-IN-1 | 0.099927974 | 0.9488 | -0.00672 |
| HCC1419 | USP7-IN-1 | 0.316 | 1.0056 | -0.00067 |
| HCC1419 | USP7-IN-1 | 0.999279741 | 1.0025 | 0.00120 |
| HCC1419 | USP7-IN-1 | 3.16 | 0.9567 | 0.00222 |
| HCC1419 | USP7-IN-1 | 9.992797406 | 0.9752 | -0.00453 |
| HCC1419 | USP7-IN-1 | 31.6 | 0.7209 | 0.00516 |
| HCC1419 | USP7-IN-1 | 50.0 | 0.4088 | 0.00827 |
| HCC1419 | Doxycycline | 0.009992797 | 0.7770 | 0.00430 |
| HCC1419 | Doxycycline | 0.0316 | 1.0764 | -0.00628 |
| HCC1419 | Doxycycline | 0.099927974 | 0.9602 | -0.00372 |
| HCC1419 | Doxycycline | 0.316 | 1.0625 | -0.00468 |
| HCC1419 | Doxycycline | 0.999279741 | 1.0708 | -0.00178 |
| HCC1419 | Doxycycline | 3.16 | 0.8973 | -0.00129 |
| HCC1419 | Doxycycline | 9.992797406 | 0.8039 | -0.00171 |
| HCC1419 | Doxycycline | 31.6 | 0.5653 | 0.01456 |
| HCC1419 | Doxycycline | 50.0 | 0.0713 | 0.03018 |