Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDXHCI002 | b-AP15 | 31.6 | -0.5737 | 0.65399 |
| PDXHCI002 | b-AP15 | 50.0 | -0.5653 | 0.40184 |
| PDXHCI002 | USP7-IN-1 | 0.009992797 | 0.9944 | 0.00644 |
| PDXHCI002 | USP7-IN-1 | 0.0316 | 1.0489 | 0.00262 |
| PDXHCI002 | USP7-IN-1 | 0.099927974 | 0.9826 | -0.00384 |
| PDXHCI002 | USP7-IN-1 | 0.316 | 0.9442 | 0.00725 |
| PDXHCI002 | USP7-IN-1 | 0.999279741 | 0.6502 | 0.08754 |
| PDXHCI002 | USP7-IN-1 | 3.16 | 0.9459 | 0.00476 |
| PDXHCI002 | USP7-IN-1 | 9.992797406 | 0.9661 | -0.00098 |
| PDXHCI002 | USP7-IN-1 | 31.6 | 0.9669 | -0.00551 |
| PDXHCI002 | USP7-IN-1 | 50.0 | 0.8827 | -0.03271 |
| PDXHCI002 | Doxycycline | 0.009992797 | 0.6755 | 0.06049 |
| PDXHCI002 | Doxycycline | 0.0316 | 1.0774 | -0.00729 |
| PDXHCI002 | Doxycycline | 0.099927974 | 1.0095 | 0.00278 |
| PDXHCI002 | Doxycycline | 0.316 | 1.0521 | -0.00490 |
| PDXHCI002 | Doxycycline | 0.999279741 | 0.9488 | -0.00909 |
| PDXHCI002 | Doxycycline | 3.16 | 0.9069 | -0.00396 |
| PDXHCI002 | Doxycycline | 9.992797406 | 0.9297 | -0.00156 |
| PDXHCI002 | Doxycycline | 31.6 | 0.8165 | 0.00040 |
| PDXHCI002 | Doxycycline | 50.0 | 0.8265 | 0.01799 |
| PDXHCI002 | GW7647 | 0.009992797 | 1.0601 | -0.00727 |
| PDXHCI002 | GW7647 | 0.0316 | 1.0272 | -0.00275 |
| PDXHCI002 | GW7647 | 0.099927974 | 0.9946 | 0.00381 |
| PDXHCI002 | GW7647 | 0.316 | 0.7474 | 0.06611 |
| PDXHCI002 | GW7647 | 0.999279741 | 1.2760 | -0.00873 |