Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-361 | 1247825-37-1 | 3.16 | 0.9976 | 0.00687 |
| MDA-MB-361 | 1247825-37-1 | 9.992797406 | 0.6473 | 0.04761 |
| MDA-MB-361 | 1247825-37-1 | 31.6 | -0.1727 | 0.30895 |
| MDA-MB-361 | 1247825-37-1 | 50.0 | -0.4648 | 0.48695 |
| MDA-MB-361 | b-AP15 | 0.009992797 | 1.1357 | 0.00223 |
| MDA-MB-361 | b-AP15 | 0.0316 | 0.9270 | 0.01337 |
| MDA-MB-361 | b-AP15 | 0.099927974 | 0.5078 | 0.09047 |
| MDA-MB-361 | b-AP15 | 0.316 | -0.1087 | 0.26898 |
| MDA-MB-361 | b-AP15 | 0.999279741 | -0.5460 | 0.48697 |
| MDA-MB-361 | b-AP15 | 3.16 | -0.5691 | 0.46355 |
| MDA-MB-361 | b-AP15 | 9.992797406 | -0.5574 | 0.61658 |
| MDA-MB-361 | b-AP15 | 31.6 | -0.6928 | 0.64069 |
| MDA-MB-361 | b-AP15 | 50.0 | -0.6324 | 0.44378 |
| MDA-MB-361 | USP7-IN-1 | 0.009992797 | 1.0356 | 0.01151 |
| MDA-MB-361 | USP7-IN-1 | 0.0316 | 1.0160 | 0.00500 |
| MDA-MB-361 | USP7-IN-1 | 0.099927974 | 0.8742 | -0.00343 |
| MDA-MB-361 | USP7-IN-1 | 0.316 | 1.0449 | 0.01281 |
| MDA-MB-361 | USP7-IN-1 | 0.999279741 | 0.5748 | 0.08569 |
| MDA-MB-361 | USP7-IN-1 | 3.16 | 1.2249 | -0.00457 |
| MDA-MB-361 | USP7-IN-1 | 9.992797406 | 0.9990 | -0.00526 |
| MDA-MB-361 | USP7-IN-1 | 31.6 | 0.6859 | 0.00859 |
| MDA-MB-361 | USP7-IN-1 | 50.0 | 0.4344 | 0.03478 |
| MDA-MB-361 | Doxycycline | 0.009992797 | 0.4003 | NaN |
| MDA-MB-361 | Doxycycline | 0.0316 | 0.9483 | -0.00477 |
| MDA-MB-361 | Doxycycline | 0.099927974 | 1.0316 | -0.00911 |