Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-231 | HY-17541A | 3.16 | 0.5326 | 0.01618 |
| MDA-MB-231 | HY-17541A | 9.992797406 | 0.1292 | 0.20541 |
| MDA-MB-231 | HY-17541A | 31.6 | -0.5762 | 0.73342 |
| MDA-MB-231 | HY-17541A | 50.0 | -0.5762 | 0.45252 |
| MDA-MB-231 | HY-17542 | 0.009992797 | 0.9646 | -0.00629 |
| MDA-MB-231 | HY-17542 | 0.0316 | 1.0001 | 0.00323 |
| MDA-MB-231 | HY-17542 | 0.099927974 | 0.9649 | -0.00442 |
| MDA-MB-231 | HY-17542 | 0.316 | 0.9978 | -0.00490 |
| MDA-MB-231 | HY-17542 | 0.999279741 | 0.7396 | 0.02316 |
| MDA-MB-231 | HY-17542 | 3.16 | 1.0800 | -0.00724 |
| MDA-MB-231 | HY-17542 | 9.992797406 | 0.9524 | 0.00478 |
| MDA-MB-231 | HY-17542 | 31.6 | 0.9912 | -0.00041 |
| MDA-MB-231 | HY-17542 | 50.0 | 0.9016 | 0.03531 |
| MDA-MB-231 | HY-50736 | 0.009992797 | 1.0024 | -0.00129 |
| MDA-MB-231 | HY-50736 | 0.0316 | 1.0752 | -0.00275 |
| MDA-MB-231 | HY-50736 | 0.099927974 | 0.9911 | -0.00214 |
| MDA-MB-231 | HY-50736 | 0.316 | 1.0094 | -0.00331 |
| MDA-MB-231 | HY-50736 | 0.999279741 | 0.6176 | 0.03764 |
| MDA-MB-231 | HY-50736 | 3.16 | -0.2610 | 0.39852 |
| MDA-MB-231 | HY-50736 | 9.992797406 | -0.4600 | 0.61881 |
| MDA-MB-231 | HY-50736 | 31.6 | -0.4598 | 0.32479 |
| MDA-MB-231 | HY-50736 | 50.0 | -0.3245 | 0.18154 |
| MDA-MB-231 | HY-50737A | 0.009992797 | 0.9998 | -0.00339 |
| MDA-MB-231 | HY-50737A | 0.0316 | 1.0063 | -0.00008 |
| MDA-MB-231 | HY-50737A | 0.099927974 | 1.0181 | -0.00289 |