Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-231 | USP7-IN-1 | 0.009992797 | 0.8481 | 0.00678 |
| MDA-MB-231 | USP7-IN-1 | 0.0316 | 1.0215 | -0.00032 |
| MDA-MB-231 | USP7-IN-1 | 0.099927974 | 1.0046 | -0.00146 |
| MDA-MB-231 | USP7-IN-1 | 0.316 | 0.9925 | 0.00248 |
| MDA-MB-231 | USP7-IN-1 | 0.999279741 | 0.8959 | 0.00763 |
| MDA-MB-231 | USP7-IN-1 | 3.16 | 0.9680 | 0.00187 |
| MDA-MB-231 | USP7-IN-1 | 9.992797406 | 1.0096 | 0.00532 |
| MDA-MB-231 | USP7-IN-1 | 31.6 | 0.8704 | 0.00723 |
| MDA-MB-231 | USP7-IN-1 | 50.0 | 0.8586 | 0.02528 |
| MDA-MB-231 | Doxycycline | 0.009992797 | 0.6049 | 0.06146 |
| MDA-MB-231 | Doxycycline | 0.0316 | 1.0279 | 0.00005 |
| MDA-MB-231 | Doxycycline | 0.099927974 | 1.0596 | -0.00207 |
| MDA-MB-231 | Doxycycline | 0.316 | 1.0807 | -0.00216 |
| MDA-MB-231 | Doxycycline | 0.999279741 | 0.9658 | -0.00041 |
| MDA-MB-231 | Doxycycline | 3.16 | 0.9123 | -0.00664 |
| MDA-MB-231 | Doxycycline | 9.992797406 | 1.0069 | 0.00890 |
| MDA-MB-231 | Doxycycline | 31.6 | 0.9330 | 0.03421 |
| MDA-MB-231 | Doxycycline | 50.0 | 0.7772 | 0.10908 |
| MDA-MB-231 | GW7647 | 0.009992797 | 1.0229 | 0.00606 |
| MDA-MB-231 | GW7647 | 0.0316 | 1.0084 | -0.00246 |
| MDA-MB-231 | GW7647 | 0.099927974 | 1.0262 | 0.00353 |
| MDA-MB-231 | GW7647 | 0.316 | 1.0360 | -0.00007 |
| MDA-MB-231 | GW7647 | 0.999279741 | 1.0550 | -0.00231 |
| MDA-MB-231 | GW7647 | 3.16 | 1.0231 | 0.00304 |
| MDA-MB-231 | GW7647 | 9.992797406 | 1.0014 | 0.00030 |