Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
MDA-MB-134-VI Mitoxantrone
3.16
 -0.9842 0.84544
MDA-MB-134-VI Mitoxantrone
9.992797406
 -0.9693 0.81198
MDA-MB-134-VI Mitoxantrone
31.6
 -0.9383 0.71264
MDA-MB-134-VI Mitoxantrone
50.0
 -0.9303 0.66220
MDA-MB-134-VI ML-323
0.009992797
 0.9787 -0.00060
MDA-MB-134-VI ML-323
0.0316
 1.1086 -0.01892
MDA-MB-134-VI ML-323
0.099927974
 1.1456 0.01131
MDA-MB-134-VI ML-323
0.316
 1.0026 0.00238
MDA-MB-134-VI ML-323
0.999279741
 0.7232 0.00382
MDA-MB-134-VI ML-323
3.16
 0.8715 0.02666
MDA-MB-134-VI ML-323
9.992797406
 0.9129 0.00317
MDA-MB-134-VI ML-323
31.6
 0.8812 0.00350
MDA-MB-134-VI ML-323
50.0
 0.3266 0.00489
MDA-MB-134-VI Pevonedistat
0.009992797
 1.0758 0.01003
MDA-MB-134-VI Pevonedistat
0.0316
 0.7501 0.03294
MDA-MB-134-VI Pevonedistat
0.099927974
 0.2813 0.09706
MDA-MB-134-VI Pevonedistat
0.316
 -0.1017 0.13705
MDA-MB-134-VI Pevonedistat
0.999279741
 -0.0248 NaN
MDA-MB-134-VI Pevonedistat
3.16
 -0.1738 0.22429
MDA-MB-134-VI Pevonedistat
9.992797406
 -0.2163 0.27165
MDA-MB-134-VI Pevonedistat
31.6
 -0.2210 0.24831
MDA-MB-134-VI Pevonedistat
50.0
 -0.1663 0.26019
MDA-MB-134-VI P22077
0.009992797
 1.0700 0.00471
MDA-MB-134-VI P22077
0.0316
 0.7526 0.00669
MDA-MB-134-VI P22077
0.099927974
 0.9188 -0.00232