Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
MCF 10A P22077
0.999279741
 0.9972 0.00204
MCF 10A P22077
3.16
 0.8933 0.36876
MCF 10A P22077
9.992797406
 -0.2181 0.65973
MCF 10A P22077
31.6
 -0.3461 0.69560
MCF 10A P22077
50.0
 -0.2119 0.14809
MCF 10A PB49673382
0.009992797
 1.0107 0.00044
MCF 10A PB49673382
0.0316
 0.9891 -0.00041
MCF 10A PB49673382
0.099927974
 1.0202 -0.00002
MCF 10A PB49673382
0.316
 0.9823 -0.00052
MCF 10A PB49673382
0.999279741
 0.9137 0.00118
MCF 10A PB49673382
3.16
 0.7486 0.00552
MCF 10A PB49673382
9.992797406
 0.2364 0.05067
MCF 10A PB49673382
31.6
 0.0770 0.09086
MCF 10A PB49673382
50.0
 0.0428 0.10768
MCF 10A Pimozide
0.009992797
 1.0082 0.00096
MCF 10A Pimozide
0.0316
 0.9830 -0.00040
MCF 10A Pimozide
0.099927974
 1.0028 -0.00065
MCF 10A Pimozide
0.316
 0.9532 0.00033
MCF 10A Pimozide
0.999279741
 0.9711 -0.00031
MCF 10A Pimozide
3.16
 0.9261 0.00146
MCF 10A Pimozide
9.992797406
 0.8301 0.00277
MCF 10A Pimozide
31.6
 -0.0175 0.31066
MCF 10A Pimozide
50.0
 -0.1385 0.48001
MCF 10A 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9919 0.00140
MCF 10A 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9879 -0.00093