Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MCF 10A | Doxycycline | 3.16 | 0.9286 | -0.00004 |
| MCF 10A | Doxycycline | 9.992797406 | 0.8265 | 0.03084 |
| MCF 10A | Doxycycline | 31.6 | 0.1643 | 0.14281 |
| MCF 10A | Doxycycline | 50.0 | 0.0611 | 0.06690 |
| MCF 10A | GW7647 | 0.009992797 | 0.9976 | -0.00039 |
| MCF 10A | GW7647 | 0.0316 | 1.0010 | 0.00090 |
| MCF 10A | GW7647 | 0.099927974 | 1.0304 | 0.00022 |
| MCF 10A | GW7647 | 0.316 | 1.0069 | 0.00108 |
| MCF 10A | GW7647 | 0.999279741 | 1.0193 | 0.00047 |
| MCF 10A | GW7647 | 3.16 | 1.0147 | 0.00090 |
| MCF 10A | GW7647 | 9.992797406 | 0.9631 | 0.00485 |
| MCF 10A | GW7647 | 31.6 | 0.1015 | 0.33214 |
| MCF 10A | GW7647 | 50.0 | -0.1219 | 0.47666 |
| MCF 10A | HBX19818 | 0.009992797 | 1.0020 | 0.00022 |
| MCF 10A | HBX19818 | 0.0316 | 0.9980 | 0.00089 |
| MCF 10A | HBX19818 | 0.099927974 | 0.9925 | 0.00107 |
| MCF 10A | HBX19818 | 0.316 | 0.9759 | -0.00014 |
| MCF 10A | HBX19818 | 0.999279741 | 0.9745 | 0.00180 |
| MCF 10A | HBX19818 | 3.16 | 0.9383 | -0.00013 |
| MCF 10A | HBX19818 | 9.992797406 | 0.8730 | 0.00028 |
| MCF 10A | HBX19818 | 31.6 | 0.5387 | 0.02709 |
| MCF 10A | HBX19818 | 50.0 | -0.1889 | 0.63364 |
| MCF 10A | HBX 41108 | 0.009992797 | 1.0007 | 0.00040 |
| MCF 10A | HBX 41108 | 0.0316 | 1.0164 | 0.00200 |
| MCF 10A | HBX 41108 | 0.099927974 | 0.9738 | -0.00061 |