Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
Hs 578T PB49673382
50.0
 0.0485 0.19929
Hs 578T Pimozide
0.009992797
 0.9862 -0.00038
Hs 578T Pimozide
0.0316
 0.7004 0.06533
Hs 578T Pimozide
0.099927974
 1.0549 -0.00441
Hs 578T Pimozide
0.316
 0.9156 0.00417
Hs 578T Pimozide
0.999279741
 0.9758 -0.00075
Hs 578T Pimozide
3.16
 0.8696 0.02246
Hs 578T Pimozide
9.992797406
 0.6644 0.05773
Hs 578T Pimozide
31.6
 -0.4944 0.71596
Hs 578T Pimozide
50.0
 -0.3708 0.62469
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 1.0931 -0.00448
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.7370 0.07054
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.1537 -0.00630
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 0.9167 0.00244
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9933 0.01295
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9890 0.00477
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 1.0418 0.00033
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 1.0424 -0.00279
Hs 578T 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0210 0.00736
Hs 578T SB1-F-21
0.009992797
 1.0803 0.00167
Hs 578T SB1-F-21
0.0316
 0.9849 0.00257
Hs 578T SB1-F-21
0.099927974
 0.9652 0.02685
Hs 578T SB1-F-21
0.316
 0.5909 0.17052
Hs 578T SB1-F-21
0.999279741
 0.1304 0.30746
Hs 578T SB1-F-21
3.16
 -0.1937 0.49407