Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0570 0.01217
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9475 -0.00167
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.8481 0.01413
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9434 -0.00142
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.7899 0.00892
HCC202 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 0.9950 0.01076
HCC202 SB1-F-21
0.009992797
 0.9538 0.00829
HCC202 SB1-F-21
0.0316
 1.1992 0.00631
HCC202 SB1-F-21
0.099927974
 1.0819 0.02119
HCC202 SB1-F-21
0.316
 0.5514 0.12411
HCC202 SB1-F-21
0.999279741
 0.0046 0.27801
HCC202 SB1-F-21
3.16
 -0.2527 0.42974
HCC202 SB1-F-21
9.992797406
 -0.5842 0.53377
HCC202 SB1-F-21
31.6
 -0.7205 0.65083
HCC202 SB1-F-21
50.0
 -0.7837 0.43556
HCC202 SB1-F-22
0.009992797
 1.0102 0.00580
HCC202 SB1-F-22
0.0316
 1.0223 0.01064
HCC202 SB1-F-22
0.099927974
 1.2190 0.01371
HCC202 SB1-F-22
0.316
 1.1221 0.01102
HCC202 SB1-F-22
0.999279741
 1.1108 0.01006
HCC202 SB1-F-22
3.16
 0.9638 0.01227
HCC202 SB1-F-22
9.992797406
 0.8904 0.03008
HCC202 SB1-F-22
31.6
 0.5158 0.06187
HCC202 SB1-F-22
50.0
 0.5140 0.01161
HCC202 SJB2-043
0.00316
 1.0115 0.00586