Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1937 | HY-17541A | 50.0 | -0.5555 | 0.46425 |
| HCC1937 | SJB3-019A | 0.999279741 | -0.5554 | 0.58281 |
| HCC1937 | Sepantronium | 3.16 | -0.5547 | 0.61884 |
| PDXHCI002 | SJB3-019A | 31.6 | -0.5546 | 0.65111 |
| PDXHCI002 | Pevonedistat | 9.992797406 | -0.5546 | 0.35857 |
| HCC1937 | MI-2 | 50.0 | -0.5533 | 0.49412 |
| T47D | Pimozide | 50.0 | -0.5532 | 0.60684 |
| HCC1954 | HBX 41108 | 31.6 | -0.5532 | 0.56180 |
| T47D | P22077 | 31.6 | -0.5532 | 0.70759 |
| Hs 578T | SJB3-019A | 0.999279741 | -0.5528 | 0.75481 |
| SK-BR-3 | Pimozide | 50.0 | -0.5520 | 0.74507 |
| SK-BR-3 | Sepantronium | 0.316 | -0.5506 | 0.72036 |
| Hs 578T | SJB3-019A | 31.6 | -0.5505 | 0.73123 |
| HCC1954 | HY-50737A | 31.6 | -0.5501 | 0.57168 |
| T47D | b-AP15 | 50.0 | -0.5499 | 0.53502 |
| HCC1937 | b-AP15 | 9.992797406 | -0.5493 | 0.61849 |
| HCC1500 | Pimozide | 50.0 | -0.5492 | 0.52625 |
| HCC1419 | Vialinin A | 50.0 | -0.5490 | 0.61758 |
| T47D | Sepantronium | 9.992797406 | -0.5487 | 0.65344 |
| PDX1258 | Sepantronium | 31.6 | -0.5472 | 0.59185 |
| BT-20 | HY-50737A | 31.6 | -0.5469 | 0.51084 |
| CAMA-1 | Sepantronium | 0.099927974 | -0.5468 | 0.63688 |
| MDA-MB-361 | Degrasyn | 31.6 | -0.5467 | 0.54627 |
| SK-BR-3 | Pimozide | 31.6 | -0.5466 | 0.70487 |
| T47D | SJB3-019A | 50.0 | -0.5465 | 0.63917 |