Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1954 | Mitoxantrone | 31.6 | -0.6799 | 0.45381 |
| HCC1954 | MI-2 | 3.16 | -0.6789 | 0.70634 |
| SK-BR-3 | MI-2 | 50.0 | -0.6785 | 0.26598 |
| CAMA-1 | Degrasyn | 31.6 | -0.6784 | 0.69296 |
| SK-BR-3 | SJB2-043 | 9.992797406 | -0.6773 | 0.78916 |
| MDA-MB-361 | Mitoxantrone | 3.16 | -0.6765 | 0.57373 |
| HCC1419 | HY-50737A | 31.6 | -0.6762 | 0.70207 |
| SK-BR-3 | Sepantronium | 31.6 | -0.6755 | 0.79210 |
| BT-20 | SB1-F-21 | 9.992797406 | -0.6752 | 0.57820 |
| Hs 578T | Mitoxantrone | 31.6 | -0.6749 | 0.86171 |
| SK-BR-3 | SJB3-019A | 31.6 | -0.6743 | 0.79372 |
| HCC1419 | HY-50736 | 31.6 | -0.6741 | 0.70594 |
| HCC1937 | P22077 | 31.6 | -0.6741 | 0.60192 |
| HCC1419 | HBX 41108 | 50.0 | -0.6735 | 0.71934 |
| HCC1428 | b-AP15 | 50.0 | -0.6735 | 0.68772 |
| HCC202 | Mitoxantrone | 3.16 | -0.6727 | 0.68447 |
| HCC202 | Degrasyn | 9.992797406 | -0.6708 | 0.57689 |
| MDA-MB-134-VI | SB1-F-21 | 50.0 | -0.6703 | 0.38015 |
| HCC1806 | HY-17541A | 50.0 | -0.6698 | 0.60494 |
| MDA-MB-231 | HBX19818 | 50.0 | -0.6695 | 0.76774 |
| PDX1258 | Mitoxantrone | 31.6 | -0.6687 | 0.67689 |
| BT-20 | Sepantronium | 0.0316 | -0.6687 | 0.64086 |
| HCC1500 | Sepantronium | 31.6 | -0.6675 | 0.52736 |
| BT-20 | b-AP15 | 9.992797406 | -0.6673 | 0.55540 |
| SK-BR-3 | b-AP15 | 9.992797406 | -0.6663 | 0.77748 |