Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-20 | SB1-F-21 | 0.099927974 | 1.0508 | -0.03800 |
| BT-20 | PB49673382 | 0.999279741 | 1.0290 | -0.03711 |
| BT-20 | SB1-F-22 | 3.16 | 1.0589 | -0.03703 |
| PDX1258 | SJB3-019A | 0.0316 | 1.1248 | -0.03676 |
| BT-20 | b-AP15 | 0.0316 | 0.8652 | -0.03556 |
| HCC1954 | STK547622 | 50.0 | 1.0881 | -0.03485 |
| CAMA-1 | STK547622 | 50.0 | 0.9782 | -0.03378 |
| BT-20 | Vialinin A | 9.992797406 | 0.1411 | -0.03371 |
| PDX1258 | GW7647 | 31.6 | 1.2214 | -0.03325 |
| PDXHCI002 | SJB2-043 | 0.316 | 0.8962 | -0.03295 |
| PDXHCI002 | USP7-IN-1 | 50.0 | 0.8827 | -0.03271 |
| HCC1954 | HY-17542 | 50.0 | 0.9541 | -0.03221 |
| HCC1954 | IU1 | 50.0 | 0.8195 | -0.03205 |
| PDXHCI002 | 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one | 50.0 | 1.1325 | -0.03164 |
| BT-20 | PB49673382 | 3.16 | 0.4896 | -0.03159 |
| BT-20 | Doxycycline | 3.16 | 0.9215 | -0.02904 |
| Hs 578T | STK547622 | 50.0 | 1.1030 | -0.02902 |
| BT-20 | Spautin-1 | 31.6 | 0.5940 | -0.02861 |
| MDA-MB-134-VI | z-VAE(OMe)-fmk | 50.0 | 0.9937 | -0.02800 |
| HCC1500 | STK547622 | 0.099927974 | 1.0305 | -0.02773 |
| PDX1258 | 1247825-37-1 | 3.16 | 1.0859 | -0.02737 |
| Hs 578T | Doxycycline | 50.0 | 1.3637 | -0.02647 |
| BT-20 | 1247825-37-1 | 0.999279741 | 1.0271 | -0.02626 |
| BT-20 | Degrasyn | 0.999279741 | 1.0023 | -0.02556 |
| HCC1954 | SJB3-019A | 0.009992797 | 1.1218 | -0.02512 |