Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-231 | STK547622 | 9.992797406 | 0.9834 | -0.00690 |
| PDX1258 | IU1 | 31.6 | 0.8477 | -0.00688 |
| PDXHCI002 | LDN57444 | 9.992797406 | 0.8698 | -0.00686 |
| HCC1419 | LDN57444 | 0.0316 | 1.1316 | -0.00686 |
| Hs 578T | GW7647 | 0.009992797 | 1.0947 | -0.00685 |
| HCC202 | HY-17542 | 50.0 | 0.6087 | -0.00685 |
| PDX1258 | Spautin-1 | 0.009992797 | 0.9266 | -0.00684 |
| BT-20 | Degrasyn | 0.0316 | 0.9185 | -0.00683 |
| HCC1428 | 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one | 0.009992797 | 0.9187 | -0.00682 |
| CAMA-1 | P22077 | 0.999279741 | 0.9769 | -0.00681 |
| MDA-MB-361 | HY-50736 | 0.009992797 | 1.2240 | -0.00680 |
| BT-20 | IU1 | 0.009992797 | 1.0990 | -0.00680 |
| HCC1937 | z-VAE(OMe)-fmk | 0.099927974 | 0.9415 | -0.00680 |
| PDX1328 | 1247825-37-1 | 0.316 | 0.8917 | -0.00679 |
| HCC1428 | z-VAE(OMe)-fmk | 0.999279741 | 0.9474 | -0.00678 |
| HCC1419 | SJB2-043 | 0.009992797 | 1.0013 | -0.00677 |
| T47D | SB1-F-22 | 0.999279741 | 0.9548 | -0.00677 |
| HCC1500 | Pimozide | 0.009992797 | 0.9454 | -0.00674 |
| PDXHCI002 | MI-2 | 0.0316 | 0.9032 | -0.00674 |
| PDX1328 | Pevonedistat | 0.0316 | 2.2642 | -0.00673 |
| HCC202 | z-VAE(OMe)-fmk | 0.0316 | 0.9822 | -0.00673 |
| HCC1428 | P22077 | 0.009992797 | 0.8895 | -0.00673 |
| HCC1428 | LDN57444 | 0.009992797 | 0.9753 | -0.00673 |
| BT-20 | 1247825-37-1 | 0.009992797 | 1.0020 | -0.00673 |
| HCC1419 | USP7-IN-1 | 0.099927974 | 0.9488 | -0.00672 |