Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-20 | SJB3-019A | 0.316 | 0.6189 | -0.06657 |
| PDXHCI002 | SB1-F-22 | 50.0 | 0.8369 | -0.06615 |
| BT-20 | HBX19818 | 9.992797406 | 1.0952 | -0.06178 |
| BT-20 | z-VAE(OMe)-fmk | 50.0 | 1.0877 | -0.06126 |
| BT-20 | HY-17542 | 50.0 | 1.0193 | -0.06083 |
| BT-20 | SB1-F-22 | 9.992797406 | 1.0616 | -0.05972 |
| BT-20 | ML-323 | 31.6 | 0.7760 | -0.05876 |
| PDX1258 | Vialinin A | 3.16 | 1.0973 | -0.05502 |
| MDA-MB-134-VI | Doxycycline | 50.0 | 0.6687 | -0.05378 |
| BT-20 | 1247825-37-1 | 3.16 | 1.1806 | -0.05261 |
| PDXHCI002 | Spautin-1 | 50.0 | 0.6896 | -0.05132 |
| PDX1328 | Pevonedistat | 0.099927974 | 4.1452 | -0.05106 |
| BT-20 | HBX19818 | 3.16 | 0.9910 | -0.05045 |
| HCC1500 | HY-17542 | 50.0 | 0.7326 | -0.04998 |
| MDA-MB-134-VI | STK547622 | 50.0 | 1.1353 | -0.04892 |
| BT-20 | Doxycycline | 31.6 | 1.0129 | -0.04764 |
| PDX1328 | Pevonedistat | 0.316 | 3.7848 | -0.04757 |
| BT-20 | STK547622 | 31.6 | 1.1526 | -0.04748 |
| BT-20 | IU1 | 0.316 | 1.1162 | -0.04672 |
| PDX1258 | SJB2-043 | 0.316 | 1.1286 | -0.04616 |
| BT-20 | ML-323 | 9.992797406 | 0.9554 | -0.04435 |
| MDA-MB-134-VI | HY-17542 | 50.0 | 0.5701 | -0.04383 |
| HCC1500 | z-VAE(OMe)-fmk | 50.0 | 1.1104 | -0.04116 |
| PDX1258 | SJB3-019A | 0.099927974 | 1.2482 | -0.04017 |
| BT-20 | STK547622 | 0.999279741 | 0.9957 | -0.03809 |