Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1954 | IU1 | 0.0316 | 1.1038 | -0.01205 |
| HCC1937 | P22077 | 0.316 | 1.0088 | -0.01201 |
| Hs 578T | z-VAE(OMe)-fmk | 50.0 | 0.9948 | -0.01198 |
| HCC1937 | HY-17541A | 0.0316 | 1.0288 | -0.01192 |
| HCC1428 | SJB2-043 | 0.00316 | 0.8875 | -0.01187 |
| HCC1500 | IU1 | 50.0 | 0.7021 | -0.01182 |
| BT-20 | USP7-IN-1 | 0.099927974 | 0.9932 | -0.01181 |
| PDX1328 | Doxycycline | 31.6 | 1.0834 | -0.01179 |
| PDX1328 | STK547622 | 0.316 | 0.5969 | -0.01174 |
| HCC202 | HBX19818 | 0.009992797 | 0.9882 | -0.01169 |
| Hs 578T | Spautin-1 | 0.0316 | 1.0443 | -0.01158 |
| HCC1428 | SB1-F-21 | 0.0316 | 0.9839 | -0.01152 |
| PDX1328 | USP7-IN-1 | 9.992797406 | 0.7110 | -0.01150 |
| SK-BR-3 | SB1-F-22 | 50.0 | 0.5492 | -0.01149 |
| MDA-MB-134-VI | HY-17542 | 31.6 | 1.0203 | -0.01142 |
| HCC1500 | HBX19818 | 0.999279741 | 1.0416 | -0.01141 |
| PDX1328 | PB49673382 | 0.0316 | 1.0555 | -0.01135 |
| MDA-MB-361 | Vialinin A | 0.0316 | 1.0291 | -0.01132 |
| PDX1328 | IU1 | 0.099927974 | 1.0010 | -0.01131 |
| MDA-MB-361 | SJB3-019A | 0.0316 | 1.0382 | -0.01123 |
| HCC1954 | Trifluoperazine | 0.009992797 | 1.0241 | -0.01122 |
| HCC1428 | Vialinin A | 0.316 | 0.9488 | -0.01120 |
| PDX1258 | Vialinin A | 0.316 | 1.0682 | -0.01120 |
| MDA-MB-361 | HBX19818 | 0.009992797 | 1.0245 | -0.01112 |
| BT-20 | Degrasyn | 0.099927974 | 1.0433 | -0.01105 |