Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1500 | IU1 | 0.099927974 | 1.3110 | 0.04008 |
| BT-20 | SJB2-043 | 0.099927974 | 1.3019 | -0.10020 |
| BT-20 | GW7647 | 31.6 | 1.2991 | -0.07036 |
| HCC202 | Pimozide | 0.099927974 | 1.2961 | -0.00634 |
| HCC202 | IU1 | 0.999279741 | 1.2959 | 0.00216 |
| PDX1328 | Pevonedistat | 0.009992797 | 1.2957 | -0.00209 |
| PDX1328 | 1247825-37-1 | 3.16 | 1.2900 | 0.00497 |
| HCC202 | LDN57444 | 3.16 | 1.2885 | 0.00710 |
| MDA-MB-134-VI | PB49673382 | 0.999279741 | 1.2840 | -0.00758 |
| MDA-MB-361 | SB1-F-22 | 0.0316 | 1.2809 | 0.00010 |
| PDXHCI002 | GW7647 | 0.999279741 | 1.2760 | -0.00873 |
| T47D | IU1 | 0.099927974 | 1.2725 | -0.00187 |
| PDX1328 | Doxycycline | 50.0 | 1.2724 | 0.00079 |
| HCC202 | PB49673382 | 0.999279741 | 1.2707 | 0.00315 |
| HCC202 | GW7647 | 0.999279741 | 1.2687 | -0.00047 |
| BT-20 | SJB2-043 | 0.009992797 | 1.2672 | -0.10846 |
| BT-20 | SJB3-019A | 0.009992797 | 1.2654 | -0.08170 |
| HCC202 | USP7-IN-1 | 0.009992797 | 1.2646 | -0.00168 |
| MDA-MB-361 | HY-17541A | 0.009992797 | 1.2632 | -0.00491 |
| PDX1258 | SJB2-043 | 0.099927974 | 1.2603 | -0.02225 |
| HCC1954 | SJB3-019A | 0.0316 | 1.2520 | -0.00955 |
| PDX1328 | SB1-F-22 | 31.6 | 1.2519 | 0.00175 |
| BT-20 | SJB3-019A | 0.0316 | 1.2497 | -0.09886 |
| PDX1258 | SJB3-019A | 0.099927974 | 1.2482 | -0.04017 |
| BT-20 | STK547622 | 9.992797406 | 1.2454 | -0.09167 |