Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDXHCI002 | SJB3-019A | 31.6 | -0.5546 | 0.65111 |
| HCC202 | SB1-F-21 | 31.6 | -0.7205 | 0.65083 |
| HCC202 | b-AP15 | 9.992797406 | -0.7694 | 0.65056 |
| HCC1428 | SJB3-019A | 0.999279741 | -0.6453 | 0.65046 |
| MDA-MB-134-VI | Trifluoperazine | 31.6 | -0.8785 | 0.65027 |
| HCC1428 | Sepantronium | 0.316 | -0.5946 | 0.65023 |
| PDX1328 | Mitoxantrone | 31.6 | -0.9642 | 0.64921 |
| HCC1954 | Sepantronium | 0.999279741 | -0.6344 | 0.64885 |
| Hs 578T | SB1-F-21 | 9.992797406 | -0.4446 | 0.64725 |
| T47D | Sepantronium | 0.999279741 | -0.4952 | 0.64682 |
| HCC1419 | HY-17541A | 31.6 | -0.5246 | 0.64676 |
| PDX1328 | SB1-F-21 | 31.6 | -0.9783 | 0.64669 |
| PDX1328 | Sepantronium | 31.6 | -0.9588 | 0.64489 |
| MCF7 | MI-2 | 31.6 | -0.3570 | 0.64381 |
| T47D | Sepantronium | 31.6 | -0.5405 | 0.64337 |
| BT-549 | MI-2 | 31.6 | -0.4518 | 0.64287 |
| MDA-MB-134-VI | SJB3-019A | 31.6 | -0.8219 | 0.64274 |
| PDXHCI002 | Degrasyn | 31.6 | -0.5716 | 0.64273 |
| HCC1937 | HY-17541A | 31.6 | -0.5214 | 0.64128 |
| BT-20 | Sepantronium | 0.0316 | -0.6687 | 0.64086 |
| T47D | SJB3-019A | 31.6 | -0.5628 | 0.64070 |
| MDA-MB-361 | b-AP15 | 31.6 | -0.6928 | 0.64069 |
| PDX1328 | SJB2-043 | 3.16 | -0.9510 | 0.63990 |
| T47D | SJB3-019A | 50.0 | -0.5465 | 0.63917 |
| MDA-MB-361 | SJB3-019A | 9.992797406 | -0.6572 | 0.63865 |