Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1500 | LDN57444 | 0.099927974 | 1.0323 | 0.02883 |
| HCC1500 | LDN57444 | 0.316 | 0.7805 | -0.00742 |
| HCC1500 | LDN57444 | 0.999279741 | 0.9461 | -0.00777 |
| HCC1500 | LDN57444 | 3.16 | 1.1308 | -0.01307 |
| HCC1500 | LDN57444 | 9.992797406 | 0.9142 | 0.01447 |
| HCC1500 | LDN57444 | 31.6 | 0.6877 | 0.15932 |
| HCC1500 | LDN57444 | 50.0 | 0.2463 | 0.02161 |
| HCC1500 | MI-2 | 0.009992797 | 1.0846 | 0.01107 |
| HCC1500 | MI-2 | 0.0316 | 0.8289 | 0.00484 |
| HCC1500 | MI-2 | 0.099927974 | 1.0707 | 0.00890 |
| HCC1500 | MI-2 | 0.316 | 0.8871 | 0.05875 |
| HCC1500 | MI-2 | 0.999279741 | 0.5526 | 0.26955 |
| HCC1500 | MI-2 | 3.16 | -0.4490 | 0.48371 |
| HCC1500 | MI-2 | 9.992797406 | -0.4125 | 0.49064 |
| HCC1500 | MI-2 | 31.6 | -0.4305 | 0.48168 |
| HCC1500 | MI-2 | 50.0 | -0.5157 | 0.29567 |
| HCC1500 | Mitoxantrone | 0.009992797 | 0.4977 | 0.12741 |
| HCC1500 | Mitoxantrone | 0.0316 | 0.2832 | 0.14882 |
| HCC1500 | Mitoxantrone | 0.099927974 | 0.1687 | 0.26331 |
| HCC1500 | Mitoxantrone | 0.316 | 0.0069 | 0.39772 |
| HCC1500 | Mitoxantrone | 0.999279741 | -0.2137 | 0.49807 |
| HCC1500 | Mitoxantrone | 3.16 | -0.2850 | 0.50359 |
| HCC1500 | Mitoxantrone | 9.992797406 | -0.3190 | 0.44816 |
| HCC1500 | Mitoxantrone | 31.6 | -0.4904 | 0.30666 |
| HCC1500 | Mitoxantrone | 50.0 | 0.0611 | -0.09801 |