Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1428 | Pevonedistat | 0.999279741 | -0.2541 | 0.13889 |
| HCC1428 | Pevonedistat | 3.16 | -0.2469 | 0.13506 |
| HCC1428 | Pevonedistat | 9.992797406 | -0.1921 | 0.14323 |
| HCC1428 | Pevonedistat | 31.6 | -0.1276 | 0.14994 |
| HCC1428 | Pevonedistat | 50.0 | -0.1563 | 0.13102 |
| HCC1428 | P22077 | 0.009992797 | 0.8895 | -0.00673 |
| HCC1428 | P22077 | 0.0316 | 0.9480 | -0.02105 |
| HCC1428 | P22077 | 0.099927974 | 0.9740 | -0.00628 |
| HCC1428 | P22077 | 0.316 | 0.9571 | -0.00314 |
| HCC1428 | P22077 | 0.999279741 | 0.9146 | 0.02213 |
| HCC1428 | P22077 | 3.16 | 0.5685 | 0.34715 |
| HCC1428 | P22077 | 9.992797406 | -0.5337 | 0.66679 |
| HCC1428 | P22077 | 31.6 | -0.7838 | 0.77650 |
| HCC1428 | P22077 | 50.0 | -0.8186 | 0.35751 |
| HCC1428 | PB49673382 | 0.009992797 | 0.9503 | -0.00543 |
| HCC1428 | PB49673382 | 0.0316 | 0.8473 | -0.00972 |
| HCC1428 | PB49673382 | 0.099927974 | 0.9420 | 0.00207 |
| HCC1428 | PB49673382 | 0.316 | 1.0218 | -0.00802 |
| HCC1428 | PB49673382 | 0.999279741 | 0.8850 | -0.00622 |
| HCC1428 | PB49673382 | 3.16 | 0.8341 | 0.00360 |
| HCC1428 | PB49673382 | 9.992797406 | 0.3177 | 0.04251 |
| HCC1428 | PB49673382 | 31.6 | 0.2112 | 0.06213 |
| HCC1428 | PB49673382 | 50.0 | -0.0082 | 0.12605 |
| HCC1428 | Pimozide | 0.009992797 | 1.1255 | -0.01650 |
| HCC1428 | Pimozide | 0.0316 | 0.9094 | -0.00766 |