Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| SK-BR-3 | 1247825-37-1 | 0.316 | 0.8955 | 0.00475 |
| SK-BR-3 | 1247825-37-1 | 0.999279741 | 0.9554 | 0.00092 |
| SK-BR-3 | 1247825-37-1 | 3.16 | 0.9414 | -0.00134 |
| SK-BR-3 | 1247825-37-1 | 9.992797406 | 0.3890 | 0.02208 |
| SK-BR-3 | 1247825-37-1 | 31.6 | -0.0647 | 0.10984 |
| SK-BR-3 | 1247825-37-1 | 50.0 | -0.0278 | 0.14874 |
| SK-BR-3 | b-AP15 | 0.009992797 | 0.9740 | 0.00580 |
| SK-BR-3 | b-AP15 | 0.0316 | 0.8340 | 0.03317 |
| SK-BR-3 | b-AP15 | 0.099927974 | 0.2866 | 0.16220 |
| SK-BR-3 | b-AP15 | 0.316 | -0.1758 | 0.34146 |
| SK-BR-3 | b-AP15 | 0.999279741 | -0.3360 | 0.49731 |
| SK-BR-3 | b-AP15 | 3.16 | -0.5251 | 0.70231 |
| SK-BR-3 | b-AP15 | 9.992797406 | -0.6663 | 0.77748 |
| SK-BR-3 | b-AP15 | 31.6 | -0.6425 | 0.77595 |
| SK-BR-3 | b-AP15 | 50.0 | -0.6241 | 0.50816 |
| SK-BR-3 | USP7-IN-1 | 0.009992797 | 1.0601 | 0.00221 |
| SK-BR-3 | USP7-IN-1 | 0.0316 | 1.0224 | 0.00220 |
| SK-BR-3 | USP7-IN-1 | 0.099927974 | 0.9119 | -0.00036 |
| SK-BR-3 | USP7-IN-1 | 0.316 | 1.1052 | -0.00153 |
| SK-BR-3 | USP7-IN-1 | 0.999279741 | 0.8715 | 0.00489 |
| SK-BR-3 | USP7-IN-1 | 3.16 | 0.9094 | 0.00877 |
| SK-BR-3 | USP7-IN-1 | 9.992797406 | 0.9076 | 0.02016 |
| SK-BR-3 | USP7-IN-1 | 31.6 | 0.8441 | 0.05783 |
| SK-BR-3 | USP7-IN-1 | 50.0 | 0.5764 | 0.06654 |
| SK-BR-3 | Doxycycline | 0.009992797 | 0.7692 | 0.01958 |